[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

[HTML][HTML] Recent strategies for nano-based PTT combined with immunotherapy: from a biomaterial point of view

X Huang, Y Lu, M Guo, S Du, N Han - Theranostics, 2021 - ncbi.nlm.nih.gov
Cancer has been a great threat to humans for decades. Due to the limitations of
monotherapy, combinational therapies such as photothermal therapy (PTT) and …

Updated analysis from KEYNOTE-189: pembrolizumab or placebo plus pemetrexed and platinum for previously untreated metastatic nonsquamous non–small-cell …

S Gadgeel, D Rodríguez-Abreu, G Speranza… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE In KEYNOTE-189, first-line pembrolizumab plus pemetrexed-platinum
significantly improved overall survival (OS) and progression-free survival (PFS) compared …

Five-year overall survival for patients with advanced non‒small-cell lung cancer treated with pembrolizumab: results from the phase I KEYNOTE-001 study

EB Garon, MD Hellmann, NA Rizvi… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE Pembrolizumab monotherapy has demonstrated durable antitumor activity in
advanced programmed death ligand 1 (PD-L1)–expressing non‒small-cell lung cancer …

Prognostic and predictive impact of circulating tumor DNA in patients with advanced cancers treated with immune checkpoint blockade

QU Zhang, J Luo, S Wu, H Si, C Gao, W Xu… - Cancer discovery, 2020 - AACR
The utility of circulating tumor DNA (ctDNA) as a biomarker in patients with advanced
cancers receiving immunotherapy is uncertain. We therefore analyzed pretreatment (n= 978) …

Predictive biomarkers for checkpoint inhibitor-based immunotherapy in hepatocellular carcinoma: where do we stand?

A Rizzo, AD Ricci, A Di Federico, G Frega… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) remains the sixth most commonly diagnosed malignancy
worldwide, still representing an important cause of cancer-related death. Over the next few …

Impact of proton pump inhibitors and histamine-2-receptor antagonists on non-small cell lung cancer immunotherapy: a systematic review and meta-analysis

A Rizzo, A Cusmai, F Giovannelli, S Acquafredda… - Cancers, 2022 - mdpi.com
Simple Summary The current meta-analysis highlighted that proton pump inhibitors (PPIs)
and histamine-2-receptor antagonists (H2RAs) could impact immune checkpoint inhibitors …

Which role for predictors of response to immune checkpoint inhibitors in hepatocellular carcinoma?

A Rizzo, A Cusmai, G Gadaleta-Caldarola… - Expert review of …, 2022 - Taylor & Francis
Introduction Hepatocellular carcinoma (HCC) remains a frequently diagnosed malignancy
worldwide, still representing an important cause of cancer-related death. Recent years have …

PD‐1/PD‐L1 blockade therapy in advanced non‐small‐cell lung cancer: current status and future directions

L Xia, Y Liu, Y Wang - The oncologist, 2019 - academic.oup.com
The use of immune checkpoint inhibitors (ICIs) has become one of the most promising
approaches in the field of cancer therapy. Unlike the current therapies that target tumor cells …

First-line immune checkpoint inhibitor-based combinations in unresectable hepatocellular carcinoma: current management and future challenges

A Rizzo, AD Ricci, G Gadaleta-Caldarola… - Expert Review of …, 2021 - Taylor & Francis
Introduction Immunotherapy has recently taken on an extremely important role in medical
oncology, as first-or later-line treatment in several tumor types, and recent years have seen …