Heavy metals exposure and Alzheimer's disease and related dementias
KM Bakulski, YA Seo, RC Hickman… - Journal of …, 2020 - content.iospress.com
Alzheimer's disease and related dementias lack effective treatment or cures and are major
public health challenges. Risk for Alzheimer's disease and related dementias is partially …
public health challenges. Risk for Alzheimer's disease and related dementias is partially …
Manganese is essential for neuronal health
KJ Horning, SW Caito, KG Tipps… - Annual review of …, 2015 - annualreviews.org
The understanding of manganese (Mn) biology, in particular its cellular regulation and role
in neurological disease, is an area of expanding interest. Mn is an essential micronutrient …
in neurological disease, is an area of expanding interest. Mn is an essential micronutrient …
The aging brain: Impact of heavy metal neurotoxicity
OM Ijomone, CW Ifenatuoha, OM Aluko… - Critical reviews in …, 2020 - Taylor & Francis
The aging process is accompanied by critical changes in cellular and molecular functions,
which upset the homeostatic balance in the central nervous system. Accumulation of metals …
which upset the homeostatic balance in the central nervous system. Accumulation of metals …
Manganese-based advanced nanoparticles for biomedical applications: future opportunity and challenges
Nanotechnology is the most promising technology to evolve in the last decade. Recent
research has shown that transition metal nanoparticles especially manganese (Mn)-based …
research has shown that transition metal nanoparticles especially manganese (Mn)-based …
[HTML][HTML] Functions of manganese in reproduction
Manganese (Mn) is the twelfth most abundant element in the earth's crust and is widely
distributed throughout the surface of the planet, naturally occurring in rocks, soil, water, and …
distributed throughout the surface of the planet, naturally occurring in rocks, soil, water, and …
SLC39A14 deficiency alters manganese homeostasis and excretion resulting in brain manganese accumulation and motor deficits in mice
S Jenkitkasemwong, A Akinyode… - Proceedings of the …, 2018 - National Acad Sciences
Solute carrier family 39, member 14 (SLC39A14) is a transmembrane transporter that can
mediate the cellular uptake of zinc, iron, and manganese (Mn). Studies of Slc39a14 …
mediate the cellular uptake of zinc, iron, and manganese (Mn). Studies of Slc39a14 …
Mechanisms of gene-environment interactions in Parkinson's disease
SM Fleming - Current environmental health reports, 2017 - Springer
Abstract Purpose of Review The purpose of the study was to discuss the main mechanisms
associated with environmental and genetic factors that contribute to the development of …
associated with environmental and genetic factors that contribute to the development of …
Manganese (II) chloride alters behavioral and neurochemical parameters in larvae and adult zebrafish
S Altenhofen, MT Wiprich, LR Nery, CE Leite… - Aquatic Toxicology, 2017 - Elsevier
Manganese (Mn) is an essential metal for organisms, but high levels can cause serious
neurological damage. The aim of this study was to evaluate the effects of MnCl 2 exposure …
neurological damage. The aim of this study was to evaluate the effects of MnCl 2 exposure …
Vitamin E protects dopaminergic neurons against manganese-induced neurotoxicity through stimulation of CHRM1 and KCNJ4
R Song, H Chen, R Zhan, M Han, L Zhao… - Journal of Trace Elements …, 2024 - Elsevier
Abstract Background Manganese (Mn) overexposure can induce neurotoxicity and lead to
manganism. Vitamin E (Vit E) has neuroprotective effects by acting as an ROS scavenger …
manganism. Vitamin E (Vit E) has neuroprotective effects by acting as an ROS scavenger …
[HTML][HTML] The cGAS-STING-mediated NLRP3 inflammasome is involved in the neurotoxicity induced by manganese exposure
J Liu, X Zhang, H Wang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Heavy metal pollution has become a global health challenge. Exposure to heavy metals
represents a major health risk. Manganese (Mn) is an essential trace element but also an …
represents a major health risk. Manganese (Mn) is an essential trace element but also an …