The international consensus classification of myeloid neoplasms and acute leukemias: myeloproliferative neoplasms

J Thiele, HM Kvasnicka, A Orazi… - American journal of …, 2023 - Wiley Online Library
A group of international experts, including hematopathologists, oncologists, and geneticists
were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World …

International Consensus Classification of myeloid and lymphoid neoplasms: myeloproliferative neoplasms

U Gianelli, J Thiele, A Orazi, N Gangat, AM Vannucchi… - Virchows Archiv, 2023 - Springer
Abstract The recently published International Consensus Classification (ICC) of myeloid
neoplasms summarized the results of an in-depth effort by pathologists, oncologists, and …

Rusfertide, a hepcidin mimetic, for control of erythrocytosis in polycythemia vera

M Kremyanskaya, AT Kuykendall… - … England Journal of …, 2024 - Mass Medical Soc
Background Polycythemia vera is a chronic myeloproliferative neoplasm characterized by
erythrocytosis. Rusfertide, an injectable peptide mimetic of the master iron regulatory …

Ruxolitinib versus best available therapy for polycythemia vera intolerant or resistant to hydroxycarbamide in a randomized trial

CN Harrison, J Nangalia, R Boucher… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Polycythemia vera (PV) is characterized by JAK/STAT activation, thrombotic/
hemorrhagic events, systemic symptoms, and disease transformation. In high-risk PV …

Neutrophil-to-lymphocyte ratio is a novel predictor of venous thrombosis in polycythemia vera

A Carobbio, AM Vannucchi, V De Stefano… - Blood cancer …, 2022 - nature.com
We investigated the neutrophil-to-lymphocyte ratio (NLR) as a predictor of thrombosis in
polycythemia vera (PV). After a median follow-up of 2.51 years, of 1508 PV patients enrolled …

Ropeginterferon versus standard therapy for low-risk patients with polycythemia vera

T Barbui, AM Vannucchi, V De Stefano… - NEJM …, 2023 - evidence.nejm.org
Background Whether phlebotomy alone can adequately maintain target hematocrit in
patients with low-risk polycythemia vera (PV) remains elusive. Methods In a phase 2 open …

JAK2 unmutated erythrocytosis: 2023 Update on diagnosis and management

N Gangat, N Szuber, A Tefferi - American journal of hematology, 2023 - Wiley Online Library
Disease Overview JAK2 unmutated or non‐polycythemia vera (PV) erythrocytosis
encompasses a heterogenous spectrum of hereditary and acquired entities. Diagnosis …

[HTML][HTML] Thrombosis in myeloproliferative neoplasms during cytoreductive and antithrombotic drug treatment

T Barbui, A Carobbio, V De Stefano - Research and Practice in Thrombosis …, 2022 - Elsevier
A state‐of‐the‐art lecture titled “Myeloproliferative Neoplasm‐associated Thrombosis” was
presented at the ISTH congress in 2021. We summarize here the main points of the lecture …

JAK2V617F variant allele frequency >50% identifies patients with polycythemia vera at high risk for venous thrombosis

P Guglielmelli, GG Loscocco, C Mannarelli… - Blood cancer …, 2021 - nature.com
Arterial (AT) and venous (VT) thrombotic events are the most common complications in
patients with polycythemia vera (PV) and are the leading causes of morbidity and mortality …

Hepcidin mimetics in polycythemia vera: resolving the irony of iron deficiency and erythrocytosis

S Handa, Y Ginzburg, R Hoffman… - Current opinion in …, 2023 - journals.lww.com
Hepcidin mimetics in polycythemia vera: resolving the irony... : Current Opinion in Hematology
Hepcidin mimetics in polycythemia vera: resolving the irony of iron deficiency and erythrocytosis …