Treatment of multiple myeloma has substantially changed over the past decade with the
introduction of several classes of new effective drugs that have greatly improved the rates …

Multiple myeloma (MM) is a haematological malignancy of plasma cells characterized by
substantial intraclonal genetic heterogeneity. Although therapeutic advances made in the …

Smoldering multiple myeloma (SMM) is an asymptomatic precursor state of multiple
myeloma (MM). Recently, MM was redefined to include biomarkers predicting a high risk of …

New approaches to stratify multiple myeloma patients based on prognosis and therapeutic
decision-making, or prediction, are needed since patients are currently managed in a similar …

Summary This International Myeloma Working Group consensus updates the disease
definition of multiple myeloma to include validated biomarkers in addition to existing …

Smoldering multiple myeloma (SMM) is an asymptomatic precursor to multiple myeloma.
Here we define the epidemiological characteristics of SMM in the general population in …

Despite significant advances in the treatment of multiple myeloma which had led to
unprecedented rates of response and survival, patients still relapse, and cure remains …

CD 38 is a multifunctional cell surface protein that has receptor as well as enzyme functions.
The protein is generally expressed at low levels on various hematological and solid tissues …

Abstract In 2014, the International Myeloma Working Group reclassified patients with
smoldering multiple myeloma (SMM) and bone marrow-plasma cell percentage (BMPC%)≥ …

Background For patients with smoldering multiple myeloma, the standard of care is
observation until symptoms develop. However, this approach does not identify high-risk …