Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …

Estrogens play an important role in the regulation of normal physiology, aging and many
disease states. Although the nuclear estrogen receptors have classically been described to …

Personalized monitoring of female hormones (for example, oestradiol) is of great interest in
fertility and women's health. However, existing approaches usually require invasive blood …

Background Early menopause is linked to an increased risk of cardiovascular disease
mortality; however, the association between early menopause and incidence and timing of …

Vascular endothelial cells (ECs) senescence correlates with the increase of cardiovascular
diseases in ageing population. Although ECs rely on glycolysis for energy production, little is …

Data from animal experiments and clinical investigations suggest that components of the
renin-angiotensin system are markedly affected by sex hormones. However, whether …

Simple Summary Human health is significantly affected by microbial infections. One of the
largest determinants of the outcomes of such infections is the host immune response. Too …

The apelin receptor (APJ; gene symbol APLNR) is a member of the G protein-coupled
receptor gene family. Neural gene expression patterns of APJ, and its cognate ligand apelin …

Estrogens, a class of steroid hormones, regulate the growth, development, and physiology of
the human reproductive system. Estrogens also involve in the neuroendocrine, skeletal …

Background Atrial fibrillation (AF) is the most common persistent cardiac arrhythmia. This
study aimed to estimate its prevalence and explore associated factors in adults aged 18 …