Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …

Type 2 diabetes is a redox disease. Oxidative stress and chronic inflammation induce a
switch of metabolic homeostatic set points, leading to glucose intolerance. Several diabetes …

Diabetes is a disorder of glucose metabolism, and over 90% are type 2 diabetes. Diabetic
cardiomyopathy (DCM) is one of the type 2 diabetes complications, usually accompanied by …

Cardiovascular diseases (CVDs) cause the largest mortality worldwide, and much attention
has been focused to unravel the mechanisms and optimize the treatment regimens …

Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …

Pyroptotic cell death or pyroptosis is characterized by caspase-1-dependent formation of
plasma membrane pores, leading to the release of pro-inflammatory cytokines and cell lysis …

Cardiovascular diseases (CVDs) are one of the leading causes of the most considerable
mortality globally, and it has been tried to find the molecular mechanisms and design new …

Macrovascular complications of diabetes, including diabetic cardiovascular disease (CVD),
occur through a number of hyperglycaemia-induced mechanisms that include generation of …

Background Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)
inflammasome is associated with metabolic disorder and cell death, which are important …

Diabetes mellitus is an extremely prevalent endocrine disease and a major global public
health concern. Diabetic complications, such as retinopathy, nephropathy, neuropathy and …