Acute myeloid leukemia (AML) is one of the most common types of leukemia in adults. While
complete remission can be obtained with intensive chemotherapy in young and fit patients …

The bone marrow (BM) microenvironment, also called the BM niche, is essential for the
maintenance of fully functional blood cell formation (hematopoiesis) throughout life. Under …

Autonomic nerves control organ function through the sympathetic and parasympathetic
branches, which have opposite effects. In the bone marrow, sympathetic (adrenergic) nerves …

Leptin receptor (LepR)‐positive cells are key components of the bone marrow hematopoietic
microenvironment, and highly enrich skeletal stem and progenitor cells that maintain …

Adult haematopoietic stem cells (HSCs) mainly reside in the bone marrow, where stromal
and haematopoietic cells regulate their function. The steady state HSC niche has been …

The mammalian hematopoietic system is remarkably efficient in meeting an organism's vital
needs, yet is highly sensitive and exquisitely regulated. Much of the organismal control over …

Abnormal hematopoiesis advances cardiovascular disease by generating excess
inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche …

The highly heterogeneous characteristics of Wharton's jelly mesenchymal stem cells (WJ‐
MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of …

Cancer relapse begins when malignant cells pass through the extreme metabolic bottleneck
of stress from chemotherapy and the byproducts of the massive cell death in the surrounding …

Estrogen receptor (ER)-positive luminal breast cancer is a subtype with generally lower risk
of metastasis to most distant organs. However, bone recurrence occurs preferentially in …