Traditional thrombolytic drugs offer limited outcomes due to short circulation half-life and low
utilization. Herein, we have designed and constructed a biological mediator-propelled …

This review highlights recent trends towards the development of in vitro multicellular systems
with definite architectures, or “organs on chips”. First, the chemical composition and …

Natural systems frequently exploit intricate multiscale and multiphasic structures to achieve
functionalities beyond those of man-made systems. Although understanding the chemical …

Stimuli-responsive materials undergo triggered changes when presented with specific
environmental cues. These dynamic systems can leverage biological signals found locally …

Injection of recombinant tissue plasminogen activator (rt-PA) is the standard drug treatment
for thrombolysis. However, rt-PA shows risk of hemorrhages and limited efficiency even at …

Over the last ten years, there has been considerable research interest in the development of
polymeric carriers for biomedicine. Such delivery systems have the potential to significantly …

Thrombotic occlusions of blood vessels are responsible for life-threatening cardiovascular
disorders such as myocardial infarction, ischemic stroke, and venous thromboembolism …

Dose control and effectiveness promotion of tissue plasminogen activator (t-PA) for
thrombolysis are vitally important to alleviate serious side effects such as hemorrhage in …

Over the last two decades, microfluidic devices have rapidly emerged as revolutionary
platforms for research and medicine. Various kinds of materials and fabrication strategies …

Vascularization, the formation of new blood vessels, is an essential biological process. As
the vasculature is involved in various fundamental physiological phenomena and closely …