Fast and effective thrombolysis using tissue plasminogen activator (tPA) is limited by the
poor delivery efficiency of thrombolytic drugs, which is induced by an interrupted …

As a paradigm shifting player of tissue engineering, organs-on-chips (OOCs) are considered
to hold great potential for future “clinical trials on chip” as well as a step forward to design …

Cardiovascular diseases claim a number of lives globally; many of which are preventable.
With the increase in diets that consist of high saturated fat, salt, and sugar, people often …

The reciprocal mechanical interaction of engineered materials with biointerfaces have long
been observed and exploited in biomedical applications. It contributes to the rise of …

A thrombus (blood clot), composed mainly of activated platelets and fibrin, obstructs arteries
or veins, leading to various life-threatening diseases. Inspired by the distinctive …

A thrombus (blood clot) is formed in injured vessels to maintain the integrity of vasculature.
However, obstruction of blood vessels by thrombosis slows blood flow, leading to death of …

The incidence of lung cancer continues to rise worldwide. Because the aggressive
metastasis of lung cancer cells is the major drawback of successful therapies, the crucial …

Cardiovascular and cerebrovascular diseases (CCVDs) describe abnormal vascular system
conditions affecting the brain and heart. Among these, ischemic heart disease and ischemic …

Bio-responsive polymers are the foundation for the construction of the smart systems that
exhibit designed biomedical functions after receiving specific stimuli such as biological …

Extracellular vesicles (EVs) are increasingly used as delivery vehicles for drugs and
bioactive molecules, which usually require intravascular administration. The endothelial …