Human immunodeficiency virus (HIV) remains a major public health concern despite a large
education effort during the past 25 years. A persistent problem with HIV infection is the high …

Thirty-three children vertically infected with human immunodeficiency virus type 1 (HIV-1),
who were born before 1985, were followed in a single center, and had reached the age of 6 …

Human immunodeficiency virus-1 (HIV-1) infection affects the striatum, resulting in gliosis
and neuronal losses. To determine whether HIV-1 proteins induce striatal neurotoxicity …

The neurodegenerative process in HIV encephalitis (HIVE) is associated with extensive
damage to the dendritic and synaptic structure that often leads to cognitive impairment …

The idea that CNS ramified microglia are quiescent has been challenged by studies that
show that microglia without the classic signs of activation can be phagocytic and appear with …

Although cells of monocytic lineage are the primary source of human immunodeficiency
virus type 1 (HIV-1) in the brain, other cell types in the central nervous system, including …

To ascertain whether viruses present at the time of primary viremia can infect the central
nervous system and to determine if microglial tropism is distinct from tropism for monocyte …

HIV-associated neurocognitive disorders (HAND) persist in the era of effective combined
antiretroviral therapy (cART). A large body of literature suggests that mitochondrial …

Infection of the brain with human immunodeficiency virus 1 (HIV-l) often leads to the
devastating loss of mental faculties. Surprisingly, HIV-1 elicits such brain dysfunction without …

Although antiretrovirals are the mainstay of therapy against HIV infection, neurological
complications associated with the virus continue to hamper quality of life of the infected …