Scaling laws in the diffusive release of neutral cargo from hollow hydrogel nanoparticles: paclitaxel-loaded poly (4-vinylpyridine)

A Moncho-Jordá, AB Jódar-Reyes, M Kanduč… - ACS …, 2020 - ACS Publications
We study the nonequilibrium diffusive release of electroneutral molecular cargo
encapsulated inside hollow hydrogel nanoparticles. We propose a theoretical model that …

Nonequilibrium uptake kinetics of molecular cargo into hollow hydrogels tuned by electrosteric interactions

A Moncho-Jorda, A Germán-Bellod… - ACS …, 2019 - ACS Publications
Hollow hydrogels represent excellent nano-and microcarriers due to their ability to
encapsulate and release large amounts of cargo molecules (cosolutes) such as reactants …

Au@ p4VP core@ shell pH-sensitive nanocomposites suitable for drug entrapment

J Clara-Rahola, A Moscoso, AB Ruiz-Muelle… - Journal of colloid and …, 2018 - Elsevier
We synthesize and characterize pH-responsive hybrid nanocomposites with SERS and drug
loading applications. This colloidal system is structured by spherical 50 nm Au cores …

Recent development of copolymeric nano-drug delivery system for Paclitaxel

S Chen, Z Song, R Feng - Anti-Cancer Agents in Medicinal …, 2020 - ingentaconnect.com
Background: Paclitaxel (PTX) has been clinically used for several years due to its good
therapeutic effect against cancers. Its poor water-solubility, non-selectivity, high cytotoxicity …

[HTML][HTML] Synthesis, characterization and antitumor activity of a poly-4-Vinyl pyridine-co-cannabidiol polymer

D Fuentes-Ríos, F Moya-Utrera, J Moreno… - European Polymer …, 2024 - Elsevier
Due to its natural origin and numerous beneficial properties, cannabidiol (CBD), one of the
major phytocannabinoids of the Cannabis sativa L., has attracted the attention of many …

Maximizing the absorption of small cosolutes inside neutral hydrogels: steric exclusion versus hydrophobic adhesion

L Pérez-Mas, A Martín-Molina… - Physical Chemistry …, 2018 - pubs.rsc.org
In this work the equilibrium absorption of nanometric cosolutes (which could represent
drugs, reactants, small globular proteins and other kind of biomacromolecules) inside …

An overview of paclitaxel delivery systems

S Kar, K Vignesh, UD Kolhe - … Technology for Natural Products Delivery Vol …, 2020 - Springer
Abstract As per the World Health Organization, cancer is the second leading cause of death
globally and is responsible for an estimated 9.6 million deaths in 2018. More than 2 million …

Crossover of the effective charge in ionic thermoresponsive hydrogel particles

A Moncho-Jordá, M Quesada-Pérez - Physical Review E, 2019 - APS
We use a generalized nonlinear Poisson-Boltzmann cell model that includes excluded-
volume effects to investigate whether the effective charge (Z eff) of charged thermosensitive …

Vascular-confined multi-passage discoidal nanoconstructs for the low-dose docetaxel inhibition of triple-negative breast cancer growth

A Felici, D Di Mascolo, M Ferreira, S Lauciello, L Bono… - Nano Research, 2022 - Springer
Taxane efficacy in triple negative breast cancer (TNBC) is limited by insufficient tumor
accumulation and severe off-target effects. Nanomedicines offer a unique opportunity to …

Novel approaches for osteosarcoma treatment: drug combination, nanotechnology and cell therapy

L Kazantseva - 2023 - riuma.uma.es
Osteosarcoma is one of the most common malignant tumours of bone, primarily affecting
children and adolescents. Although the implementation of chemotherapy and radiotherapy …