Background Neural tube defects (NTDs) are debilitating birth defects involving the central
nervous system (CNS). Despite recent advances, NTDs represent the second most common …

The formation of the embryonic brain and spinal cord begins as the neural plate bends to
form the neural folds, which meet and adhere to close the neural tube. The neural ectoderm …

Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …

Neural tube defects (NTDs), including anencephaly and spina bifida, are common major
malformations of fetal development resulting from incomplete closure of the neural tube …

Exciting new features have been described concerning neurogenic bowel dysfunction,
including interactions between the central nervous system, the enteric nervous system …

Background The aim of this study was to assess sex differences in major congenital
anomaly (CA) diagnoses within a national population sample; to examine the influence of …

Incidence Worldwide, the incidence of neural tube defects (NTDs) varies from 0.17 to 6.39
per 1,000 live births. The declining prevalence of myelomeningocele, the most common …

Abstract Background Neural tube defects (NTDs) are common birth defects (~ 1 in 1000
pregnancies in the US and Europe) that have complex origins, including environmental and …

Spina bifida is one of the most common neural tube defects (NTDs) with a complex etiology.
Variants in planar cell polarity (PCP) genes have been associated with NTDs including …

Neural tube defects (NTDs) represent a failure of the neural plate to complete the
developmental transition to a neural tube. NTDs are the most common birth anomaly of the …