Astrocytes are specialized non-neuronal glial cells of the central nervous system,
contributing to neuronal excitability and synaptic transmission (gliotransmission). Astrocytes …

Astrocytes have been in the limelight of active research for about 3 decades now. Over this
period, ideas about their function and role in the nervous system have evolved from simple …

Epilepsy is a common brain disorder, characterized by spontaneous recurrent seizures, with
associated neuropsychiatric and cognitive comorbidities and increased mortality. Although …

Alterations in the extracellular matrix are common in patients with epilepsy and animal
models of epilepsy, yet whether they are the cause or consequence of seizures and epilepsy …

Epilepsy is a chronic, relapsing neurological disorder, and current treatments focus primarily
on neurons, yet one-third of patients still develop drug-resistant epilepsy. Therefore, there is …

Epilepsy is a chronic condition characterized by recurrent spontaneous seizures. The
interaction between astrocytes and neurons has been suggested to play a role in the …

The central nervous system (CNS) exhibits remarkable adaptability throughout life, enabled
by intricate interactions between neurons and glial cells, in particular, oligodendrocytes …

Background Epilepsy initiation involves multifactorial etiologies, including genetic
susceptibility, structural anomalies, and glial cell dysregulations, particularly in astrocytes …

Scavenger receptor class B type I (SR-BI) is abundant in adult mouse and human brains, but
its function in the central nervous system (CNS) remains unclear. This study explored the …

Alterations in the extracellular matrix (ECM) are common in epilepsy, yet whether they are
cause or consequence of disease is unknow. Using Theiler's virus infection model of …