Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

Neuropsychiatric involvement of SLE includes a variety of symptoms that impact quality of
life and patient prognosis. There have been recent advances in improving the diagnosis of …

It took decades to arrive at the general consensus dismissing the notion that the immune
system is independent of the central nervous system. In the case of uncontrolled systemic …

Study design issues related to patient selection (non-NPSLE vs. NPSLE syndromes, SLE
disease activity, medications) are critical for biomarker development. Regional and network …

For people with chronic autoimmune rheumatic diseases (AIRD), such as rheumatoid
arthritis (RA), systemic lupus erythematosus (SLE) or systemic sclerosis (SSc), normal …

Background Despite its potentially significant impact on disease outcome, peripheral
nervous system involvement in systemic lupus erythematosus has received little attention …

Objective We aimed to evaluate all-cause and cause-specific mortality in patients with
systemic lupus erythematosus (SLE) and neuropsychiatric (NP) symptoms in the …

Introduction Juvenile systemic lupus erythematosus (j-SLE) is a rare chronic autoimmune
disease affecting multiple organs. Ranging from minor features, such as headache or mild …

Neuropsychiatric manifestations are highly prevalent in systemic lupus erythematosus (SLE)-
patients. We aimed to unravel the substrates of these manifestations by investigating …

Currently, the evaluation of mental disorders in patients with Systemic lupus erythematosus
(SLE) is essential in the management of the illness because of their impact in morbimortality …