Targeting innate immunity-driven inflammation in CKD and cardiovascular disease

T Speer, S Dimmeler, SJ Schunk, D Fliser… - Nature Reviews …, 2022 - nature.com
Mortality among patients with chronic kidney disease (CKD) is largely a consequence of
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …

Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives

DM Tanase, EM Gosav, MI Anton, M Floria… - Biomolecules, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most debilitating chronic diseases worldwide, with
increased prevalence and incidence. In addition to its macrovascular damage, through its …

Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease

Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

The roles of gut microbiota and its metabolites in diabetic nephropathy

H Zhao, CE Yang, T Liu, MX Zhang, Y Niu… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which
increases the risk of renal failure and causes a high global disease burden. Due to the lack …

A review of therapeutic impacts of saffron (Crocus sativus L.) and its constituents

F Anaeigoudari, A Anaeigoudari… - Physiological …, 2023 - Wiley Online Library
Application of herbal medicines in the treatment of diseases is in the center of attention of
medical scientific societies. Saffron (Cricus sativus L.) is a medicinal plant belonging to the …

Diabetic nephropathy: significance of determining oxidative stress and opportunities for antioxidant therapies

M Darenskaya, S Kolesnikov, N Semenova… - International Journal of …, 2023 - mdpi.com
Diabetes mellitus (DM) belongs to the category of socially significant diseases with epidemic
rates of increases in prevalence. Diabetic nephropathy (DN) is a specific kind of kidney …

[HTML][HTML] Sodium-glucose cotransporter 2 (SGLT2) inhibitors: benefits versus risk

B Jasleen, GK Vishal, M Sameera, M Fahad, S Deion… - Cureus, 2023 - ncbi.nlm.nih.gov
With the growing burden of metabolic disease, cardiovascular disease, and diabetes
mellitus, there is an implication for new pharmacological intervention. Sodium-glucose …

The effect of sodium-glucose cotransporter 2 inhibitors on biomarkers of inflammation: A systematic review and meta-analysis of randomized controlled trials

D Wang, J Liu, L Zhong, S Li, L Zhou… - Frontiers in …, 2022 - frontiersin.org
Aims: Inflammatory biomarkers may play vital roles in the pathophysiology of diabetes and
diabetic cardiorenal complications. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have …

Oxidative stress as a culprit in diabetic kidney disease

S Su, Z Ma, H Wu, Z Xu, H Yi - Life Sciences, 2023 - Elsevier
Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …

Prognosis and risk factors of chronic kidney disease progression in patients with diabetic kidney disease and non-diabetic kidney disease: a prospective cohort CKD …

S Chen, L Chen, H Jiang - Renal failure, 2022 - Taylor & Francis
Diabetic kidney disease (DKD) is emerging rapidly as the leading cause of chronic kidney
disease (CKD) worldwide. In this 3-year prospective, multicenter cohort study, a total of 1138 …