Biogenesis, isolation, and detection of exosomes and their potential in therapeutics and Diagnostics
The increasing research and rapid developments in the field of exosomes provide insights
into their role and significance in human health. Exosomes derived from various sources …
into their role and significance in human health. Exosomes derived from various sources …
Structural, kinetic, and thermodynamic aspects of insulin aggregation
Given the significance of protein aggregation in proteinopathies and the development of
therapeutic protein pharmaceuticals, revamped interest in assessing and modelling the …
therapeutic protein pharmaceuticals, revamped interest in assessing and modelling the …
Polymer-mediated Protein/Peptide Therapeutic Stabilization: Current Progress and Future Directions
RP Sivasankaran, K Snell, G Kunkel, P Georgiou… - Progress in Polymer …, 2024 - Elsevier
Proteins and peptides have played a pivotal role in revolutionizing disease treatment over
the last century. Despite their commercial success, protein therapeutics can be eliminated or …
the last century. Despite their commercial success, protein therapeutics can be eliminated or …
Unfolding of the SARS-CoV-2 spike protein through infrared and ultraviolet-C radiation based disinfection
The spreading of coronavirus from contacting surfaces and aerosols created a pandemic
around the world. To prevent the transmission of SARS-CoV-2 virus and other contagious …
around the world. To prevent the transmission of SARS-CoV-2 virus and other contagious …
[HTML][HTML] Experimental procedures to investigate fibrillation of proteins
The unwanted phenomenon of protein fibrillation is observed in vivo and during therapeutic
protein development in the industry. Protein aggregation is associated with various …
protein development in the industry. Protein aggregation is associated with various …
Insulin fibrillation under physicochemical parameters of bioprocessing and intervention by peptides and surface-active agents
C Panda, S Kumar, S Gupta… - Critical Reviews in …, 2024 - Taylor & Francis
Even after the centenary celebration of insulin discovery, there prevail challenges
concerning insulin aggregation, not only after repeated administration but also during …
concerning insulin aggregation, not only after repeated administration but also during …
Effects of Lactobacillus plantarum-fermented soy whey composite/huajiao seed antimicrobial peptides/inulin composites on konjac gel preservation
Z Xiao, X Huang, Z Liu, J Xie, Z Rasheed, J Yan… - Food Packaging and …, 2024 - Elsevier
To extend the shelf life of konjac gels, this study investigated the effects of preservatives
prepared using food production byproducts. First, the ultrasonic and microwave-assisted …
prepared using food production byproducts. First, the ultrasonic and microwave-assisted …
Optimizing a therapeutic humanized follicle‐stimulating hormone–blocking antibody formulation by protein thermal shift assay
Biopharmaceutical products are formulated using several Food and Drug Administration
(FDA) approved excipients within the inactive ingredient limit to maintain their storage …
(FDA) approved excipients within the inactive ingredient limit to maintain their storage …
[HTML][HTML] Lyophilization of biomimetic amyloids preserves their regulatable, endocrine-like functions for nanoparticle release
MTP Favaro, H López-Laguna, E Voltà-Durán… - Applied Materials …, 2024 - Elsevier
The secretory granules from the mammalian endocrine system are functional amyloids that
act as dynamic depots to store and release protein hormones into the bloodstream. The …
act as dynamic depots to store and release protein hormones into the bloodstream. The …
Natural lipopeptide surfactin inhibits insulin aggregation and prevents amyloid-induced cytotoxicity and inflammation
Despite the centennial of the pioneering discovery of insulin, challenges regarding insulin
aggregation at the site of repeated injection, as well as during industrial production, storage …
aggregation at the site of repeated injection, as well as during industrial production, storage …