Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice

JF Cryan, C Mombereau, A Vassout - Neuroscience & Biobehavioral …, 2005 - Elsevier
Since its introduction almost 20 years ago, the tail suspension test has become one of the
most widely used models for assessing antidepressant-like activity in mice. The test is based …

Twenty-five years of research on medicinal plants in Latin America: a personal view

JB Calixto - Journal of ethnopharmacology, 2005 - Elsevier
In this short article, I have discussed (on the base of the Web of Science data base search),
the expressive progress of Latin American scientific production in peer review journals in the …

Guarana: revisiting a highly caffeinated plant from the Amazon

FC Schimpl, JF da Silva… - Journal of …, 2013 - Elsevier
Abstract Ethnopharmacological relevance Guarana (Paullinia cupana Kunth var. sorbilis
(Mart.) Ducke) has been traditionally consumed by indigenous communities of the Amazon …

The effects of curcumin on depressive-like behaviors in mice

Y Xu, BS Ku, HY Yao, YH Lin, X Ma, YH Zhang… - European journal of …, 2005 - Elsevier
Curcuma longa is a major constituent of Xiaoyao-san, the traditional Chinese medicinal
formula, which has been used effectively to treat depression-related diseases in China …

[HTML][HTML] Paullinia cupana: a multipurpose plant–a review

LLM Marques, EDF Ferreira, MN de Paula… - Revista Brasileira de …, 2019 - Elsevier
Seeds of guarana (Paullinia cupana Kunth, Sapindaceae) feature diverse pharmacological
functions, for example, antimicrobial, antioxidant, anticarcinogenic, stimulating, and …

Brazilian plants as possible adaptogens: an ethnopharmacological survey of books edited in Brazil

FR Mendes, EA Carlini - Journal of Ethnopharmacology, 2007 - Elsevier
In a survey, from Brazilian books, we searched plants that are in popular use for purposes
resembling those of an adaptogen. This study focused on 24 books by authors from diverse …

Anxiolytic-, antidepressant-and anticonvulsant-like effects of the alkaloid montanine isolated from Hippeastrum vittatum

AFS Da Silva, JP De Andrade, LRM Bevilaqua… - Pharmacology …, 2006 - Elsevier
Compounds isolated from different members of the Amaryllidaceae family are becoming
relevant options for the treatment of neurological disorders and neurodegenerative …

N-palmitoylethanolamide, an endocannabinoid, exhibits antidepressant effects in the forced swim test and the tail suspension test in mice

HL Yu, XQ Deng, YJ Li, YC Li, ZS Quan… - Pharmacological Reports, 2011 - Springer
The antidepressant-like effects of N-palmitoylethanolamide (PEA), a putative
endocannabinoid, was investigated in mice using the tail suspension test (TST) and the …

The traditional use of native brazilian plants for male sexual dysfunction: Evidence from ethnomedicinal applications, animal models, and possible mechanisms of …

TM Teixeira, DD Boeff, L de Oliveira Carvalho… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Sexual dysfunction is a multifactorial health condition
characterized by distressing disturbances in the sexual response and libido, leading to an …