Idiopathic pulmonary fibrosis: Current and future treatment

DS Glass, D Grossfeld, HA Renna… - The clinical …, 2022 - Wiley Online Library
Objectives Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease characterized
by dry cough, fatigue, and progressive exertional dyspnea. Lung parenchyma and …

Progressive pulmonary fibrosis: an expert group consensus statement

SK Rajan, V Cottin, R Dhar, S Danoff… - European …, 2023 - Eur Respiratory Soc
This expert group consensus statement emphasises the need for standardising the definition
of progressive fibrosing interstitial lung diseases (F-ILDs), with an accurate initial diagnosis …

Survival in adult lung transplantation: where are we in 2020?

S Bos, R Vos, DE Van Raemdonck… - Current opinion in …, 2020 - journals.lww.com
Lung transplantation offers a survival benefit in well chosen patients with end-stage lung
diseases. However, CLAD, side effects of immunosuppressive therapy and solid organ …

Idiopathic pulmonary fibrosis: Molecular mechanisms and potential treatment approaches

DS Glass, D Grossfeld, HA Renna, P Agarwala… - Respiratory …, 2020 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease with high mortality that
commonly occurs in middle-aged and older adults. IPF, characterized by a decline in lung …

Medical treatments for idiopathic pulmonary fibrosis: a systematic review and network meta-analysis

T Pitre, J Mah, W Helmeczi, MF Khalid, S Cui, M Zhang… - Thorax, 2022 - thorax.bmj.com
Background Idiopathic pulmonary fibrosis (IPF) is a respiratory disorder with a poor
prognosis. Our objective is to assess the comparative effectiveness of 22 approved or …

Small extracellular vesicles from menstrual blood-derived mesenchymal stem cells (MenSCs) as a novel therapeutic impetus in regenerative medicine

L Chen, J Qu, Q Mei, X Chen, Y Fang, L Chen… - Stem Cell Research & …, 2021 - Springer
Menstrual blood-derived mesenchymal stem cells (MenSCs) have great potential in
regenerative medicine. MenSC has received increasing attention owing to its impressive …

Targeting TGF-β/periostin signaling by sesamol ameliorates pulmonary fibrosis and improves lung function and survival

SK Tirunavalli, M Kuncha, R Sistla… - The Journal of Nutritional …, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disorder that severely impairs
lung function, by increasing lung stiffness. Sesamol, a phenolic Phyto-molecule isolated …

Cell therapy strategies for COVID-19: Current approaches and potential applications

MM Zaki, E Lesha, K Said, K Kiaee… - Science …, 2021 - science.org
Coronavirus disease 2019 (COVID-19) continues to burden society worldwide. Despite most
patients having a mild course, severe presentations have limited treatment options. COVID …

Gene therapy strategies for idiopathic pulmonary fibrosis: recent advances, current challenges, and future directions

MJR Ruigrok, HW Frijlink, BN Melgert, P Olinga… - … Therapy-Methods & …, 2021 - cell.com
Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which the lungs become
irreversibly scarred, leading to declining lung function. As currently available drugs do not …

Engineering ferroptosis inhibitors as inhalable nanomedicines for the highly efficient treatment of idiopathic pulmonary fibrosis

M Guo, T Peng, C Wu, X Pan, Z Huang - Bioengineering, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) refers to chronic progressive fibrotic interstitial
pneumonia. It is called a “tumor-like disease” and cannot be cured using existing clinical …