Asthma in adults
G Mosnaim - New England Journal of Medicine, 2023 - Mass Medical Soc
Key Clinical Points Asthma in Adults Asthma guidelines state that a definitive diagnosis of
asthma should be based on the presence of characteristic respiratory symptoms such as …
asthma should be based on the presence of characteristic respiratory symptoms such as …
Disease-modifying anti-asthmatic drugs
M Lommatzsch, GG Brusselle, GW Canonica… - The Lancet, 2022 - thelancet.com
Drugs available for asthma treatment in the first decades of the 20th century
(sympathomimetic agents such as oral ephedrine, intravenous adrenaline, or inhaled …
(sympathomimetic agents such as oral ephedrine, intravenous adrenaline, or inhaled …
Translating evidence to optimize patient care using GRADE
Optimal evidence-based clinical practice requires systematic summaries of the best
available evidence, including ratings of the quality of that evidence, and is facilitated by the …
available evidence, including ratings of the quality of that evidence, and is facilitated by the …
The 5T approach in asthma: triple therapy targeting treatable traits
Using a therapeutic strategy that is free from traditional diagnostic labels and based on the
identification of “treatable traits”(TTs), which are influential in clinical presentations in each …
identification of “treatable traits”(TTs), which are influential in clinical presentations in each …
Single inhaler triple therapy (SITT) in asthma: Systematic review and practice implications
A significant number of patients with asthma remain uncontrolled despite treatment with
inhaled corticosteroids (ICS) and long‐acting β2 adrenergic bronchodilators (LABA). The …
inhaled corticosteroids (ICS) and long‐acting β2 adrenergic bronchodilators (LABA). The …
Revisiting asthma pharmacotherapy: where do we stand and where do we want to go?
M Cazzola, CP Page, MG Matera… - European …, 2023 - Eur Respiratory Soc
Several current guidelines/strategies outline a treatment approach to asthma, which
primarily consider the goals of improving lung function and quality of life and reducing …
primarily consider the goals of improving lung function and quality of life and reducing …
Individualized aerosol medicine: Integrating device into the patient
Pulmonary drug delivery is complex due to several challenges including disease-, patient-,
and clinicians-related factors. Although many inhaled medications are available in aerosol …
and clinicians-related factors. Although many inhaled medications are available in aerosol …
Treatable traits, combination inhaler therapy and the future of asthma management
PG Gibson, VM McDonald, D Thomas - Respirology, 2023 - Wiley Online Library
The landscape of asthma has considerably changed in the last decade. Effective
medications and inhaler devices have been developed and integrated into the asthma …
medications and inhaler devices have been developed and integrated into the asthma …
Benefits of LAMA in patients with asthma-COPD overlap: a systematic review and meta-analysis
J Qin, G Wang, D Han - Clinical Immunology, 2022 - Elsevier
Purpose A systematic review and meta-analysis to determine the efficacy of long-acting
muscarinic antagonist (LAMA) in patients with asthma-COPD overlap (ACO) was conducted …
muscarinic antagonist (LAMA) in patients with asthma-COPD overlap (ACO) was conducted …
[HTML][HTML] The TL1A-DR3 axis in asthma: membrane-bound and secreted TL1A co-determined the development of airway remodeling
J Zhang, D Zhang, Y Pan, X Liu, J Xu… - Allergy, Asthma & …, 2022 - ncbi.nlm.nih.gov
Purpose Tumor necrosis factor-like ligand 1A (TL1A), especially its secreted form, has been
shown to contribute to eosinophilic inflammation and mucus production, cardinal features of …
shown to contribute to eosinophilic inflammation and mucus production, cardinal features of …