Mechanisms and management of thyroid disease and atrial fibrillation: impact of atrial electrical remodeling and cardiac fibrosis
A Takawale, M Aguilar, Y Bouchrit, R Hiram - Cells, 2022 - mdpi.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia associated with increased
cardiovascular morbidity and mortality. The pathophysiology of AF is characterized by …
cardiovascular morbidity and mortality. The pathophysiology of AF is characterized by …
Atrial fibrillation from the pathologist's perspective
D Corradi - Cardiovascular pathology, 2014 - Elsevier
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
Thyroid hormones inhibit TGF-β signaling and attenuate fibrotic responses
E Alonso-Merino, R Martin Orozco… - Proceedings of the …, 2016 - National Acad Sciences
TGF-β, the most potent profibrogenic factor, acts by activating SMAD (mothers against
decapentaplegic) transcription factors, which bind to SMAD-binding elements in target …
decapentaplegic) transcription factors, which bind to SMAD-binding elements in target …
[HTML][HTML] Ibrutinib displays atrial-specific toxicity in human stem cell-derived cardiomyocytes
S Shafaattalab, E Lin, E Christidi, H Huang, Y Nartiss… - Stem Cell Reports, 2019 - cell.com
Ibrutinib (IB) is an oral Bruton's tyrosine kinase (BTK) inhibitor that has demonstrated benefit
in B cell cancers, but is associated with a dramatic increase in atrial fibrillation (AF). We …
in B cell cancers, but is associated with a dramatic increase in atrial fibrillation (AF). We …
New aspects of endocrine control of atrial fibrillation and possibilities for clinical translation
Hormones are potent endo-, para-, and autocrine endogenous regulators of the function of
multiple organs, including the heart. Endocrine dysfunction promotes a number of …
multiple organs, including the heart. Endocrine dysfunction promotes a number of …
Atrial metabolism and tissue perfusion as determinants of electrical and structural remodelling in atrial fibrillation
D Opacic, KA van Bragt, HM Nasrallah… - Cardiovascular …, 2016 - academic.oup.com
Atrial fibrillation (AF) is the most common tachyarrhythmia in clinical practice. Over decades
of research, a vast amount of knowledge has been gathered about the causes and …
of research, a vast amount of knowledge has been gathered about the causes and …
Effects of thyroid dysfunction and the thyroid-stimulating hormone levels on the risk of atrial fibrillation: a systematic review and dose-response meta-analysis from …
M Huang, S Yang, G Ge, H Zhi, L Wang - Endocrine Practice, 2022 - Elsevier
Objective To explore the relationship between thyroid dysfunction, thyroid-stimulating
hormone (TSH) levels, and risks of atrial fibrillation (AF) in studies and conduct a dose …
hormone (TSH) levels, and risks of atrial fibrillation (AF) in studies and conduct a dose …
Minor perturbations of thyroid homeostasis and major cardiovascular endpoints—Physiological mechanisms and clinical evidence
P Müller, MKS Leow, JW Dietrich - Frontiers in Cardiovascular …, 2022 - frontiersin.org
It is well established that thyroid dysfunction is linked to an increased risk of cardiovascular
morbidity and mortality. The pleiotropic action of thyroid hormones strongly impacts the …
morbidity and mortality. The pleiotropic action of thyroid hormones strongly impacts the …
Impact of thyroid status on incident kidney dysfunction and chronic kidney disease progression in a nationally representative cohort
AS You, K Kalantar-Zadeh, GA Brent, Y Narasaki… - Mayo Clinic …, 2024 - Elsevier
Objective To examine the relationship between thyroid status and incident kidney
dysfunction/chronic kidney disease (CKD) progression. Patients and Methods We examined …
dysfunction/chronic kidney disease (CKD) progression. Patients and Methods We examined …
Thyroid gland dysfunction and its effect on the cardiovascular system: a comprehensive review of the literature
N Ahmadi, F Ahmadi, M Sadiqi… - Endokrynologia …, 2020 - journals.viamedica.pl
There is an intimate and functional relationship between the cardiovascular system and the
thyroid gland; from sharing the same embryologic origin to modulating each of the …
thyroid gland; from sharing the same embryologic origin to modulating each of the …