Interferon-induced transmembrane protein 3 (IFITM3) and its antiviral activity
I Jimenez-Munguia, AH Beaven, PS Blank… - Current Opinion in …, 2022 - Elsevier
Infections caused by enveloped viruses require fusion with cellular membranes for viral
genome entry. Viral entry occurs following an interaction of viral and cellular membranes …
genome entry. Viral entry occurs following an interaction of viral and cellular membranes …
Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques
Visualization of cellular dynamics using fluorescent light microscopy has become a reliable
and indispensable source of experimental evidence for biological studies. Over the past two …
and indispensable source of experimental evidence for biological studies. Over the past two …
[HTML][HTML] Event-triggered STED imaging
Monitoring the proteins and lipids that mediate all cellular processes requires imaging
methods with increased spatial and temporal resolution. STED (stimulated emission …
methods with increased spatial and temporal resolution. STED (stimulated emission …
Lipids and secretory vesicle exocytosis
IO Akefe, SL Osborne, B Matthews, TP Wallis… - Molecular Mechanisms …, 2023 - Springer
In recent years, the number of studies implicating lipids in the regulation of synaptic vesicle
exocytosis has risen considerably. It has become increasingly clear that lipids such as …
exocytosis has risen considerably. It has become increasingly clear that lipids such as …
[HTML][HTML] Channels and transporters of the pulmonary lamellar body in health and disease
P Dietl, M Frick - Cells, 2021 - mdpi.com
The lamellar body (LB) of the alveolar type II (ATII) cell is a lysosome-related organelle
(LRO) that contains surfactant, a complex mix of mainly lipids and specific surfactant …
(LRO) that contains surfactant, a complex mix of mainly lipids and specific surfactant …
Regulated exocytosis from astrocytes: a matter of vesicles?
C Calì - Frontiers in Neuroscience, 2024 - frontiersin.org
The presence of secretory vesicles (synaptic-like microvesicles or SLMVs) in astrocytes
capable of fine-tuning synaptic transmission, has been a topic of debate in the field. While …
capable of fine-tuning synaptic transmission, has been a topic of debate in the field. While …
Simulated dynamic cholesterol redistribution favors membrane fusion pore constriction
Endo-and exocytosis proceed through a highly strained membrane fusion pore topology
regardless of the aiding protein machinery. The membrane's lipid components bias fusion …
regardless of the aiding protein machinery. The membrane's lipid components bias fusion …
PI(4,5)P2 and Cholesterol: Synthesis, Regulation, and Functions
A Rosenhouse-Dantsker, D Gazgalis… - … and PI (4, 5) P2 in Vital …, 2023 - Springer
Abstract Phosphatidylinositol 4, 5-bisphosphate (PI (4, 5) P2) is the most abundant
membrane phosphoinositide and cholesterol is an essential component of the plasma …
membrane phosphoinositide and cholesterol is an essential component of the plasma …
[HTML][HTML] Sequestration of membrane cholesterol by cholesterol-binding proteins inhibits SARS-CoV-2 entry into Vero E6 cells
M Kulma, A Šakanović, A Bedina-Zavec… - Biochemical and …, 2024 - Elsevier
Membrane lipids and proteins form dynamic domains crucial for physiological and
pathophysiological processes, including viral infection. Many plasma membrane proteins …
pathophysiological processes, including viral infection. Many plasma membrane proteins …
Barriers to exocytotic vesicle discharge
Regulated exocytosis, a universal process of eukaryotic cells, involves the merging between
the vesicle membrane and the plasma membrane, plays a key role in cell-to-cell …
the vesicle membrane and the plasma membrane, plays a key role in cell-to-cell …