The diversity, composition, and function of the bacterial community inhabiting the human
gastrointestinal tract contributes to host health through its role in producing energy or …

Despite milestones in preventive measures and treatment, cardiovascular disease (CVD)
remains associated with a high burden of morbidity and mortality. The protracted nature of …

Tobacco smoking is positively correlated with non-alcoholic fatty liver disease (NAFLD),,,–,
but the underlying mechanism for this association is unclear. Here we report that nicotine …

Parabacteroides distasonis (P. distasonis) plays an important role in human health,
including diabetes, colorectal cancer and inflammatory bowel disease. Here, we show that …

Cardiometabolic disease (CMD), characterized with metabolic disorder triggered
cardiovascular events, is a leading cause of death and disability. Metabolic disorders trigger …

Ceramides are a heterogeneous group of bioactive membrane sphingolipids that play
specialized regulatory roles in cellular metabolism depending on their characteristic fatty …

A strong correlation between gut microbes and host health has been observed in numerous
gut metagenomic cohort studies. However, the underlying mechanisms governing host …

Growing evidence suggests that ceramides play an important role in the development of
atherosclerotic and valvular heart disease. Ceramides are biologically active sphingolipids …

Nonalcoholic fatty liver disease (NAFLD), a series of liver metabolic disorders manifested by
lipid accumulation within hepatocytes, has become the primary cause of chronic liver …

Cardiovascular diseases, the notorious killer, are mainly caused by atherosclerosis (AS)
characterized by lipids, cholesterol, and iron overload in plaques. Macrophages are effector …