Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

Rationale X-ray velocimetry (XV) has been utilized in preclinical models to assess lung
motion and regional ventilation, though no studies have compared XV-derived physiologic …

Lung cancer (LC) is the most common cause of cancer death, with 75% of cases being
diagnosed in late stages. This study aimed to determine potential miRNAs as biomarkers for …

Background Coexisting obstructive sleep apnoea (OSA) in patients with COPD, defined as
overlap syndrome (OVS), is prevalent and underdiagnosed. Routine assessment of OSA is …

Background Stereotactic ablative radiotherapy (SABR) is the standard treatment for
medically inoperable early-stage non-small cell lung cancer (ES-NSCLC), but which …

The most common oncogenic driver mutations for non–small cell lung cancer (NSCLC)
activate EGFR or KRAS. Clinical trials exploring treatments for EGFR-or KRAS-mutated …

Background Cancer is widely regarded as a complex disease primarily driven by genetic
mutations. A critical concern and significant obstacle lies in discerning driver genes amid an …

Simple Summary A growing amount of evidence points out that patients with chronic
respiratory disease have an increased risk of lung cancer. We conducted a systematic …

Chronic obstructive pulmonary disease (COPD) is a well-known and established risk factor
for lung cancer development. COPD and lung cancer share common several pathogenic …

Chronic obstructive pulmonary disease (COPD) is an independent risk factor for the
development of lung cancer. Several pathogenic pathways such as oxidative stress and …