Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

Normothermic machine perfusion (NMP) technologies are emerging as an important adjunct
in organ preservation and transplantation. NMP can enable the reduction or avoidance of …

Background Deceased donor kidneys are preserved in cold hypoxic conditions. Providing
oxygen during preservation might improve post-transplant outcomes, particularly for kidneys …

With the aim to explore innovative tools for organ preservation, especially in marginal
organs, we hereby describe a clinical trial of ex-vivo hypothermic oxygenated perfusion …

Importance Continuous hypothermic machine perfusion during organ preservation has a
beneficial effect on graft function and survival in kidney transplant when compared with static …

The increased utilization of high-risk renal grafts for transplantation requires optimization of
pretransplant organ assessment strategies. Current decision-making methods to accept an …

Background. Hypothermic machine perfusion (HMP) has become standard care in many
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …

The use of cold preservation solutions to rapidly flush and cool the kidney followed by static
cold storage in ice has been the standard kidney preservation technique for the last 50 y …

The high demand for organs in kidney transplantation and the expansion of the donor pool
have led to the widespread implementation of machine perfusion technologies. In this study …

Background Supplemental oxygenation of the standard hypothermic machine perfusion
(HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing …