Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive …

A Valavanidis, T Vlachogianni, K Fiotakis… - International journal of …, 2013 - mdpi.com
Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory
system increase the production of mediators of pulmonary inflammation and initiate or …

Antioxidants and human diseases

P Rajendran, N Nandakumar, T Rengarajan… - Clinica chimica acta, 2014 - Elsevier
Oxidative stress plays a pivotal role in the development of human diseases. Reactive
oxygen species (ROS) that includes hydrogen peroxide, hyphochlorus acid, superoxide …

Regulation of inflammation in cancer by eicosanoids

ER Greene, S Huang, CN Serhan… - Prostaglandins & other lipid …, 2011 - Elsevier
Inflammation in the tumor microenvironment is now recognized as one of the hallmarks of
cancer. Endogenously produced lipid autacoids, locally acting small molecule lipid …

Phospholipase A2 Drives Tumorigenesis and Cancer Aggressiveness through Its Interaction with Annexin A1

L Vecchi, TG Araujo, FVPV Azevedo, STS Mota… - Cells, 2021 - mdpi.com
Phospholipids are suggested to drive tumorigenesis through their essential role in
inflammation. Phospholipase A2 (PLA2) is a phospholipid metabolizing enzyme that …

Tumor accomplice: T cell exhaustion induced by chronic inflammation

L Fang, K Liu, C Liu, X Wang, W Ma, W Xu… - Frontiers in …, 2022 - frontiersin.org
The development and response to treatment of tumor are modulated by inflammation, and
chronic inflammation promotes tumor progression and therapy resistance. This article …

Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia

XJ Yan, I Dozmorov, W Li… - Blood, The Journal …, 2011 - ashpublications.org
Individual cytokines and groups of cytokines that might represent networks in chronic
lymphocytic leukemia (CLL) were analyzed and their prognostic values determined. Serum …

LPLUNC1 suppresses IL-6-induced nasopharyngeal carcinoma cell proliferation via inhibiting the Stat3 activation

Q Liao, Z Zeng, X Guo, X Li, F Wei, W Zhang, P Chen… - Oncogene, 2014 - nature.com
Abstract Tumor-associated macrophage (TAM)-related chronic inflammation and interleukin-
6 (IL-6) contribute to the progression of nasopharyngeal carcinoma (NPC). In this study, we …

miRNA in macrophage development and function

S Roy - Antioxidants & Redox Signaling, 2016 - liebertpub.com
Significance: MicroRNAs (miRNAs) control cellular gene expression via primarily binding to
3′ or 5′ untranslated region of the target transcript leading to translational repression or …

Molecular mechanisms of anticancer effects of Glucosamine

F Zahedipour, R Dalirfardouei, G Karimi… - Biomedicine & …, 2017 - Elsevier
Glucosamine is an amino sugar that is produced naturally in human body. It is an essential
carbohydrate component of many cellular glycoproteins, glycolipids, and …

Flavonoids derived from Anemarrhenae Rhizoma ameliorate inflammation of benign prostatic hyperplasia via modulating COX/LOX pathways

X Cao, Y Shang, W Kong, S Jiang, J Liao… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Flavonoids are the main components of the traditional
Chinese medicine Anemarrhenae Rhizoma (dried rhizome of Anemarrhena asphodeloides …