Diarrheagenic Escherichia coli

JP Nataro, JB Kaper - Clinical microbiology reviews, 1998 - Am Soc Microbiol
Escherichia coli is the predominant nonpathogenic facultative flora of the human intestine.
Some E. coli strains, however, have developed the ability to cause disease of the …

Iron acquisition systems of gram-negative bacterial pathogens define TonB-dependent pathways to novel antibiotics

PE Klebba, SMC Newton, DA Six, A Kumar… - Chemical …, 2021 - ACS Publications
Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

Rapid and Simple Determination of theEscherichia coli Phylogenetic Group

O Clermont, S Bonacorsi, E Bingen - Applied and environmental …, 2000 - Am Soc Microbiol
Phylogenetic analysis has shown that Escherichia coli is composed of four main
phylogenetic groups (A, B1, B2, and D) and that virulent extra-intestinal strains mainly …

Pathogenicity assessment of Shiga toxin‐producing Escherichia coli (STEC) and the public health risk posed by contamination of food with STEC

EFSA Biohaz Panel, K Koutsoumanis, A Allende… - Efsa …, 2020 - Wiley Online Library
The provisional molecular approach, proposed by EFSA in 2013, for the pathogenicity
assessment of Shiga toxin‐producing Escherichia coli (STEC) has been reviewed. Analysis …

Complete Genome Sequence of Enterohemorrhagic Eschelichia coli O157:H7 and Genomic Comparison with a Laboratory Strain K-12

T Hayashi, K Makino, M Ohnishi, K Kurokawa… - DNA …, 2001 - academic.oup.com
Escherichia coli O157: H7 is a major food-borne infectious pathogen that causes diarrhea,
hemorrhagic colitis, and hemolytic uremic syndrome. Here we report the complete …

Iron and oxidative stress in bacteria

D Touati - Archives of biochemistry and biophysics, 2000 - Elsevier
The appearance of oxygen on earth led to two major problems: the production of potentially
deleterious reactive oxygen species and a drastic decrease in iron availability. In addition …

[HTML][HTML] Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment

S Whelan, B Lucey, K Finn - Microorganisms, 2023 - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections, especially
among women and older adults, leading to a significant global healthcare cost burden …

[HTML][HTML] Shared and distinct mechanisms of iron acquisition by bacterial and fungal pathogens of humans

M Caza, JW Kronstad - Frontiers in cellular and infection microbiology, 2013 - frontiersin.org
Iron is the most abundant transition metal in the human body and its bioavailability is
stringently controlled. In particular, iron is tightly bound to host proteins such as transferrin to …

Sequestration and scavenging of iron in infection

NL Parrow, RE Fleming, MF Minnick - Infection and immunity, 2013 - Am Soc Microbiol
The proliferative capability of many invasive pathogens is limited by the bioavailability of
iron. Pathogens have thus developed strategies to obtain iron from their host organisms. In …

Association of Genomic O Island 122 of Escherichia coli EDL 933 with Verocytotoxin-Producing Escherichia coli Seropathotypes That Are Linked to Epidemic and/or …

MA Karmali, M Mascarenhas, S Shen… - Journal of clinical …, 2003 - Am Soc Microbiol
The distribution of EDL 933 O island 122 (OI-122) was investigated in 70 strains of
Verocytotoxin-producing Escherichia coli (VTEC) of multiple serotypes that were classified …