Impact of direct‐acting antiviral regimens on mortality and morbidity outcomes in patients with chronic hepatitis C: systematic review and meta‐analysis

Y Sahakyan, V Lee‐Kim, KE Bremner… - Journal of Viral …, 2021 - Wiley Online Library
The long‐term effects of direct‐acting antiviral therapies (DAAs) for chronic hepatitis C
(CHC) remain uncertain. The objective of this systematic review and meta‐analysis was to …

Computational analysis for identification of early diagnostic biomarkers and prognostic biomarkers of liver cancer based on GEO and TCGA databases and studies on …

S Gao, J Gang, M Yu, G Xin, H Tan - BMC cancer, 2021 - Springer
Background Liver cancer is the sixth most commonly diagnosed cancer and the fourth most
common cause of cancer death. The purpose of this work is to find new diagnostic …

Tertiary prevention of HCC in chronic hepatitis B or C infected patients

W Teng, YC Liu, WJ Jeng, CW Su - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) recurrence is the major obstacle
concerning patients' survival. Tertiary prevention by antiviral therapies could reduce HCC …

Correlation of LAGE3 with unfavorable prognosis and promoting tumor development in HCC via PI3K/AKT/mTOR and Ras/RAF/MAPK pathways

Y Li, H Xiong - BMC cancer, 2022 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most common clinical
malignancies quite susceptible to recurrence and metastasis. Despite several improvements …

HBx and c-MYC cooperate to induce URI1 expression in HBV-related hepatocellular carcinoma

H Tsuchiya, M Amisaki, A Takenaga, S Honjo… - International journal of …, 2019 - mdpi.com
Unconventional prefoldin RNA polymerase II subunit 5 interactor (URI1) has emerged as an
oncogenic driver in hepatocellular carcinoma (HCC). Although the hepatitis B virus (HBV) …

miR-135b-5p suppresses androgen receptor-enhanced hepatocellular carcinoma cell proliferation via regulating the HIF-2α/c-Myc/P27 signals in vitro

S Bao, C Wang, S Jin, K Hu, J Lu - OncoTargets and therapy, 2020 - Taylor & Francis
Introduction Hepatocellular carcinoma (HCC) accounts for more than 90% of liver cancers
and is ranked as the fifth most common malignancy. Androgen receptor (AR) may promote …

Serum miR-885-5p can be used as a marker for efficacy prediction and prognosis of advanced liver cancer

K Wang - Cellular and Molecular Biology, 2020 - cellmolbiol.org
This study set out to observe the value of miR-885-5p in the prognosis evaluation of liver
cancer patients after transcatheter arterial chemoembolization. Sixty liver cancer patients …

Identification of novel lncRNAs for detection of HBV-associated hepatocellular carcinoma

Y Li, X Chen, H Huang, G Li, L Liao, T Yuan… - OncoTargets and …, 2019 - Taylor & Francis
Purpose This study was conducted to investigate the differentially expressed profiles of long
non-coding RNAs (lncRNAs) in HBV-associated HCC (HBV-HCC), which may serve as …

[HTML][HTML] Brazilian Society of Hepatology Updated Recommendations for Systemic Treatment of Hepatocellular Carcinoma

AL Chagas, CRG Leal, VB Mello… - Arquivos de …, 2023 - SciELO Brasil
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality
worldwide. The Brazilian Society of Hepatology (SBH) published in 2020 the updated …

Reduced IκBα promotes hepatocellular carcinoma cell proliferation and migration via regulation of NF‑κB/Erbin axis

Y Tan, XT Lin, YD Luo, J Zhang, L Fang… - Oncology …, 2020 - spandidos-publications.com
Aberrantly low expression of NF‑κB inhibitor α (IκBα) is observed in hepatocellular
carcinoma (HCC), yet the underlying mechanism via which IκBα regulates HCC remains …