Galectins, a family of glycan-binding proteins, are well-known for their role in shaping the
immune microenvironment. They can directly affect the activity and survival of different …

The fundamental role of cell adhesion molecules in mediating various biological processes
as angiogenesis has been well-documented. CD146, an adhesion molecule of the …

Obesity and its related complications pose an increasing threat to human health; however,
targetable obesity‐related membrane receptors are not yet elucidated. Here, the membrane …

Simple Summary Uveal melanoma (UM) is a rare aggressive eye cancer. Although
treatment of the eye tumour is successful, about 50% of UM patients develop a relapse of …

Changes in cell growth and metabolism are affected by the surrounding environmental
factors to adapt to the cell's most appropriate growth model. However, abnormal cell …

Angiogenesis, the growth of new blood vessels out of existing vessels, is a complex and
tightly regulated process. It is executed by the cells that cover the inner surface of the …

The poor prognosis of hepatocellular carcinoma (HCC) is mainly because of its high rate of
metastasis. Thus, elucidation of the molecular mechanisms underlying HCC metastasis is of …

Galectin-3 is a galactoside-binding protein that is commonly overexpressed in many
epithelial cancers. It is increasingly recognized as a multi-functional, multi-mode promoter in …

Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …

Recently, we involved the carbohydrate-binding protein Galectin-3 (Gal-3) as a druggable
target for KRAS-mutant-addicted lung and pancreatic cancers. Here, using glioblastoma …