Angiopoietin‐2 (ANGPT2) is a prognostic factor in metastatic colorectal cancer (CRC).
Nevertheless, it remains to be elucidated which molecular characteristics make up the …

Cerebral malaria (CM) is a life-threatening diffuse encephalopathy caused by Plasmodium
falciparum, in which the destruction of the blood–brain barrier (BBB) is the main cause of …

Endomucin (EMCN) is the type I transmembrane glycoprotein, mucin-like component of the
endothelial cell glycocalyx. We have previously shown that EMCN is necessary for vascular …

Abstract Galectin-3 (Gal-3) binds to cell adhesion glycoprotein CD146 to promote cytokine
secretion and mediate endothelial cell migration. Here, we used Nuclear Magnetic …

Melanoma is a highly aggressive skin cancer with poor outcomes associated with distant
metastasis. Intrinsic properties of melanoma cells alongside the crosstalk between …

Galectins and cytokines are both secreted proteins whose levels are prognosis factors for
several cancers. Extracellular galectins bind to the glycans decorating glycoproteins and are …

CD146 (MCAM, MUC18, S-Endo1) is a transmembrane glycoprotein belonging to both CAM
and mucin families. It exists as different splice variants and is cleaved from the membrane by …

Hepatocellular carcinoma (HCC) is always accompanied by persistent inflammation of liver
tissues, which is considered to exert protumourigenic effects by promoting cancer growth …

The effects of endocrine-disrupting compounds (EDCs) on the placenta, a critical gestational
organ for xenobiotic protection, are well reported; however, models to determine the role of …

Here, we investigated the role of the cell membrane protein CD 146 in galectin‐3‐mediated
endothelial cell migration at the molecular level. Our results show that knocking down CD …