[HTML][HTML] Multipotent stromal cells: one name, multiple identities
Multipotent stromal cells (MSCs) are vital for development, maintenance, function, and
regeneration of most tissues. They can differentiate along multiple connective lineages, but …
regeneration of most tissues. They can differentiate along multiple connective lineages, but …
[HTML][HTML] Immunomodulatory properties of mesenchymal stem cells/dental stem cells and their therapeutic applications
Mesenchymal stem/stromal cells (MSCs) are widely distributed in the body and play
essential roles in tissue regeneration and homeostasis. MSCs can be isolated from …
essential roles in tissue regeneration and homeostasis. MSCs can be isolated from …
[HTML][HTML] Impact of cryopreservation and freeze-thawing on therapeutic properties of mesenchymal stromal/stem cells and other common cellular therapeutics
C Cottle, AP Porter, A Lipat, C Turner-Lyles… - Current stem cell …, 2022 - Springer
Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …
procedures–short “freeze-thawing”–are among the final steps in economically viable …
[HTML][HTML] Immunomodulatory mechanisms and therapeutic potential of mesenchymal stem cells
G Yang, X Fan, Y Liu, P Jie, M Mazhar, Y Liu… - Stem Cell Reviews and …, 2023 - Springer
Mesenchymal stem cells (MSCs) are regarded as highly promising cells for allogeneic cell
therapy, owing to their multipotent nature and ability to display potent and varied functions in …
therapy, owing to their multipotent nature and ability to display potent and varied functions in …
[HTML][HTML] Current perspectives on mesenchymal stromal cell therapy for graft versus host disease
Graft versus host disease (GvHD) is the clinical condition in which bone marrow-derived
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …
[HTML][HTML] Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success
Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …
Single‐cell and spatial transcriptomics decodes Wharton's jelly‐derived mesenchymal stem cells heterogeneity and a subpopulation with wound repair signatures
P Chen, S Tang, M Li, D Wang, C Chen… - Advanced …, 2023 - Wiley Online Library
The highly heterogeneous characteristics of Wharton's jelly mesenchymal stem cells (WJ‐
MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of …
MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of …
[HTML][HTML] ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression
G Ye, J Li, W Yu, Z Xie, G Zheng, W Liu… - … & Molecular Medicine, 2023 - nature.com
Improving health and delaying aging is the focus of medical research. Previous studies have
shown that mesenchymal stem cell (MSC) senescence is closely related to organic aging …
shown that mesenchymal stem cell (MSC) senescence is closely related to organic aging …
[HTML][HTML] Extracellular vesicles: emerging roles, biomarkers and therapeutic strategies in fibrotic diseases
J Zhu, S Wang, D Yang, W Xu, H Qian - Journal of Nanobiotechnology, 2023 - Springer
Extracellular vesicles (EVs), a cluster of cell-secreted lipid bilayer nanoscale particles,
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
universally exist in body fluids, as well as cell and tissue culture supernatants. Over the past …
Perinatal hyperoxia and developmental consequences on the lung‐brain axis
S Obst, J Herz, MA Alejandre Alcazar… - Oxidative medicine …, 2022 - Wiley Online Library
Approximately 11.1% of all newborns worldwide are born preterm. Improved neonatal
intensive care significantly increased survival rates over the last decades but failed to …
intensive care significantly increased survival rates over the last decades but failed to …