Metabolomics: small molecules that matter more
BC Muthubharathi, T Gowripriya, K Balamurugan - Molecular omics, 2021 - pubs.rsc.org
Metabolomics, an analytical study with high-throughput profiling, helps to understand
interactions within a biological system. Small molecules, called metabolites or metabolomes …
interactions within a biological system. Small molecules, called metabolites or metabolomes …
Promises and pitfalls of untargeted metabolomics
I Gertsman, BA Barshop - Journal of inherited metabolic disease, 2018 - Springer
Metabolomics is one of the newer omics fields, and has enabled researchers to complement
genomic and protein level analysis of disease with both semi-quantitative and quantitative …
genomic and protein level analysis of disease with both semi-quantitative and quantitative …
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
Although it has long been recognized that the enteric community of bacteria that inhabit the
human distal intestinal track broadly impacts human health, the biochemical details that …
human distal intestinal track broadly impacts human health, the biochemical details that …
Global metabolic profiling procedures for urine using UPLC–MS
The production of'global'metabolite profiles involves measuring low molecular-weight
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …
metabolites (< 1 kDa) in complex biofluids/tissues to study perturbations in response to …
Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative …
AM Evans, CD DeHaven, T Barrett, M Mitchell… - Analytical …, 2009 - ACS Publications
To address the challenges associated with metabolomics analyses, such as identification of
chemical structures and elimination of experimental artifacts, we developed a platform that …
chemical structures and elimination of experimental artifacts, we developed a platform that …
[HTML][HTML] Applications of machine learning in metabolomics: Disease modeling and classification
A Galal, M Talal, A Moustafa - Frontiers in genetics, 2022 - frontiersin.org
Metabolomics research has recently gained popularity because it enables the study of
biological traits at the biochemical level and, as a result, can directly reveal what occurs in a …
biological traits at the biochemical level and, as a result, can directly reveal what occurs in a …
Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry
D Vuckovic - Analytical and bioanalytical chemistry, 2012 - Springer
The choice of sample-preparation method is extremely important in metabolomic studies
because it affects both the observed metabolite content and biological interpretation of the …
because it affects both the observed metabolite content and biological interpretation of the …
[HTML][HTML] Defining the metabolome: size, flux, and regulation
Renewed interest in metabolic research over the last two decades has inspired an explosion
of technological developments for studying metabolism. At the forefront of methodological …
of technological developments for studying metabolism. At the forefront of methodological …
HILIC‐MS for metabolomics: An attractive and complementary approach to RPLC‐MS
Hydrophilic interaction chromatography (HILIC) is an emerging separation mode of liquid
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …
Clinical applications of metabolomics in oncology: a review
JL Spratlin, NJ Serkova, SG Eckhardt - Clinical cancer research, 2009 - AACR
Metabolomics, an omic science in systems biology, is the global quantitative assessment of
endogenous metabolites within a biological system. Either individually or grouped as a …
endogenous metabolites within a biological system. Either individually or grouped as a …