Hyperdiploidy is the largest genetic entity B-cell precursor acute lymphoblastic leukemia in
children. The diagnostic hallmark of its two variants that will be discussed in detail herein is …

Intrachromosomal amplification of chromosome 21 defines a subtype of high-risk childhood
acute lymphoblastic leukemia (iAMP21-ALL) characterized by copy number changes and …

The mutational landscape of B-cell precursor acute lymphoblastic leukemia (BCP-ALL), the
most common pediatric cancer, is not fully described partially because commonly applied …

A better understanding of ABL1 kinase domain mutation–independent causes of tyrosine
kinase inhibitor (TKI) resistance is needed for BCR:: ABL1–positive B-cell precursor acute …

Deciphering the structural variation across tumour genomes is crucial to determine the
events driving tumour progression and better understand tumour adaptation and evolution …

Acute lymphoblastic leukemia (ALL) is characterized by the presence of chromosomal
changes, including numerical changes, translocations, and deletions, which are often …

B cell acute lymphoblastic leukemia (ALL) is characterized by the highly heterogeneity of
pathogenic genetic background, and there are still approximately 30–40% of patients …

Cancer is an aberrant growth of cells with dynamic molecular changes as the disease
progresses. As a result of these dynamic changes and an increase in cellular plasticity …

Oral cancer presents a significant clinical challenge due to the presence of hidden lymph
node metastases, which greatly influence treatment decisions. Advances in detection …

Clonal heterogeneity and genomic evolution in intrachromosomal amplification of
chromosome 21: A case report Clonal heterogeneity and genomic evolution in …