Raman spectroscopy: an emerging tool in neurodegenerative disease research and diagnosis
G Devitt, K Howard, A Mudher… - ACS chemical …, 2018 - ACS Publications
The pathogenesis underlining many neurodegenerative diseases remains incompletely
understood. The lack of effective biomarkers and disease preventative medicine demands …
understood. The lack of effective biomarkers and disease preventative medicine demands …
Raman spectroscopy on brain disorders: transition from fundamental research to clinical applications
Brain disorders such as brain tumors and neurodegenerative diseases (NDs) are
accompanied by chemical alterations in the tissues. Early diagnosis of these diseases will …
accompanied by chemical alterations in the tissues. Early diagnosis of these diseases will …
Raman spectroscopy: techniques and applications in the life sciences
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
Label-free imaging of amyloid plaques in Alzheimer's disease with stimulated Raman scattering microscopy
M Ji, M Arbel, L Zhang, CW Freudiger, SS Hou… - Science …, 2018 - science.org
One of the key pathological features of Alzheimer's disease (AD) is the existence of
extracellular deposition of amyloid plaques formed with misfolded amyloid-β (Aβ). The …
extracellular deposition of amyloid plaques formed with misfolded amyloid-β (Aβ). The …
Raman spectroscopy to distinguish grey matter, necrosis, and glioblastoma multiforme in frozen tissue sections
SN Kalkanis, RE Kast, ML Rosenblum… - Journal of neuro …, 2014 - Springer
The need exists for a highly accurate, efficient and inexpensive tool to distinguish normal
brain tissue from glioblastoma multiforme (GBM) and necrosis boundaries rapidly, in real …
brain tissue from glioblastoma multiforme (GBM) and necrosis boundaries rapidly, in real …
Raman spectroscopic imaging for in vivo detection of cerebral brain metastases
M Kirsch, G Schackert, R Salzer, C Krafft - Analytical and bioanalytical …, 2010 - Springer
We report for the first time a proof-of-concept experiment employing Raman spectroscopy to
detect intracerebral tumors in vivo by brain surface mapping. Raman spectroscopy is a non …
detect intracerebral tumors in vivo by brain surface mapping. Raman spectroscopy is a non …
Rapid biomarker screening of Alzheimer's disease by interpretable machine learning and graphene-assisted Raman spectroscopy
The study of Alzheimer's disease (AD), the most common cause of dementia, faces
challenges in terms of understanding the cause, monitoring the pathogenesis, and …
challenges in terms of understanding the cause, monitoring the pathogenesis, and …
Viscoelasticity of amyloid plaques in transgenic mouse brain studied by Brillouin microspectroscopy and correlative Raman analysis
Amyloidopathy is one of the most prominent hallmarks of Alzheimer's disease (AD), the
leading cause of dementia worldwide, and is characterized by the accumulation of amyloid …
leading cause of dementia worldwide, and is characterized by the accumulation of amyloid …
Plaque-associated lipids in Alzheimer's diseased brain tissue visualized by nonlinear microscopy
By simultaneous coherent anti-Stokes Raman scattering (CARS) and 2-photon fluorescence
microscopy of Thioflavin-S stained Alzheimer´ s diseased human brain tissues, we show …
microscopy of Thioflavin-S stained Alzheimer´ s diseased human brain tissues, we show …
Slow excitotoxicity in Alzheimer's disease
Progress is being made in identifying possible pathogenic factors and novel genes in the
development of Alzheimer's disease (AD). Many of these could contribute to 'slow …
development of Alzheimer's disease (AD). Many of these could contribute to 'slow …