[HTML][HTML] Insights into hepatocellular carcinoma in patients with thalassemia: from pathophysiology to novel therapies

PC Lin, WY Hsu, PY Lee, SH Hsu… - International Journal of …, 2023 - mdpi.com
Thalassemia is a heterogeneous congenital hemoglobinopathy common in the
Mediterranean region, Middle East, Indian subcontinent, and Southeast Asia with increasing …

Biomarker discovery in hepatocellular carcinoma (HCC) for personalized treatment and enhanced prognosis

B Yu, W Ma - Cytokine & Growth Factor Reviews, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a leading contributor to cancer-related deaths worldwide
and presents significant challenges in diagnosis and treatment due to its heterogeneous …

[HTML][HTML] Application of Machine Learning Techniques to Assess Alpha-Fetoprotein at Diagnosis of Hepatocellular Carcinoma

S Gil-Rojas, M Suárez, P Martínez-Blanco… - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and is associated
with high mortality rates. Approximately 80% of cases occur in cirrhotic livers, posing a …

[HTML][HTML] Cuproptosis-and m6A-Related lncRNAs for prognosis of hepatocellular carcinoma

Y Zhu, JK Tan, JA Goon - Biology, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is known for its poor prognosis, but the
markers for prognosis still remain unclear to date. This study focused on the long non-coding …

Integrative analysis reveals that SLC38A1 promotes hepatocellular carcinoma development via PI3K/AKT/mTOR signaling via glutamine mediated energy metabolism

H Feng, C Wu, G Zhong, J Gong, C Miao… - Journal of Cancer …, 2023 - Springer
Although hepatocellular carcinoma (HCC) is rather frequent, little is known about the
molecular pathways underlying its development, progression, and prognosis. In the current …

The p53 Family of Transcription Factors Represses the Alpha-fetoprotein Gene Expression in Hepatocellular Carcinoma

C Kunst, K Gulow, M Müller… - … and Liver Diseases, 2023 - epub.uni-regensburg.de
Background: p53 deletion and mutation as well as upregulation of alpha-fetoprotein (AFP)
are hallmarks of hepatocarcinogenesis. p63 and p73 belong to the family of p53-related …

[HTML][HTML] CENPB promotes the proliferation of hepatocellular carcinoma and is directly regulated by miR-29a

X Wang, L Luo, Y Zhang, G Liu, Z Fang, Z Xu… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a significant global health concern as it ranks as the
sixth most common malignant tumor and the third leading cause of cancer-related deaths. In …

[HTML][HTML] Immune checkpoint inhibition (ICI) in current systemic therapies for hepatocellular carcinoma (HCC)

F van Bömmel, T Berg, F Lordick - ESMO Gastrointestinal Oncology, 2023 - Elsevier
Immune checkpoint inhibition (ICI) has revolutionized cancer therapy, including treatment of
hepatocellular carcinoma (HCC) which comprises 80%-90% of all liver cancers, the third …

Utility of a microRNA panel in diagnosis and prognosis of hepatitis C–associated hepatocellular carcinoma

AA ALrefai, SK Rizk, AK Khamis, ZA Kasemy… - Laboratory …, 2024 - academic.oup.com
Background Hepatocellular carcinoma (HCC) is the most common type of primary liver
cancer and the leading cause of cancer mortality. Various studies have linked dysregulated …

MicroRNA let-7c-5p Alleviates in Hepatocellular Carcinoma by Targeting Enhancer of Zeste Homolog 2: A Study Intersecting Bioinformatic Analysis and Validated …

T Lin, X Guo, Q Du, W Liu, X Zhong… - Critical Reviews™ in …, 2024 - dl.begellhouse.com
Enhancer of zeste homolog 2 (EZH2) gene has a prognostic role in hepatocellular
carcinoma (HCC). This study aimed to identify the role of microRNAs (miRNAs) let-7c-5p by …