Our understanding of the function of the transcriptional regulators YAP and TAZ (YAP/TAZ)
in cancer is advancing. In this Review, we provide an update on recent progress in YAP/TAZ …

ROCK belongs to the AGC family of Ser/Thr protein kinases that are involved in many
cellular processes. ROCK-driven actomyosin contractility regulates cytoskeletal dynamics …

Non–small lung cancers (NSCLC) frequently (∼ 30%) harbor KRAS driver mutations, half of
which are KRAS G12C. KRAS-mutant NSCLC with comutated STK11 and/or KEAP1 is …

RAS and RHO GTPases function as signaling nodes that regulate diverse cellular
processes. Whereas RAS mutations were identified in human cancers nearly four decades …

Increased vascular calcification (VC) is observed in patients with cardiovascular diseases
such as atherosclerosis, diabetes, and chronic kidney disease. VC is divided into three types …

Introduction Currently, cancer immunotherapy is widely used as a groundbreaking method
that can completely cure advanced cancers. However, this new immunotherapy has the …

O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a dynamic post-translational
modification that regulates thousands of proteins and almost all cellular processes. Aberrant …

Cell migration is crucial for efficient immune responses and is aberrantly used by cancer
cells during metastatic dissemination. Amoeboid migrating cells use myosin II-powered …

Myocardial infarction in the absence of obstructive coronary artery disease (MINOCA) is an
important subtype of myocardial infarction. Although comprising less than 50% stenosis in …

Coronavirus disease COVID-19, which is caused by severe acute respiratory syndrome
coronavirus SARS-CoV-2, has become a worldwide pandemic in recent years. In addition to …