The discovery of leptin changed the view of adipose tissue from that of a passive vessel that
stores fat to that of a dynamic endocrine organ that actively regulates behaviour and …

Anorexia nervosa is a psychiatric disorder characterized by altered body image, persistent
food restriction and low body weight, and is associated with global endocrine dysregulation …

A moderate elevation of thyrotropin (TSH) concentrations, which is associated with
triiodothyronine (T3) values in or slightly above the upper normal range, is frequently found …

Purpose: To review recent advances in the pathophysiology and potential clinical
applications of leptin, an adipose tissue-derived hormone. Data Sources: A MEDLINE …

Context: Although women with anorexia nervosa (AN) have severe depletion of body fat, a
paradoxical increase in bone marrow fat has been described. Recent data suggest that …

To examine the hypothesis that normalization of low circulating leptin levels in patients with
anorexia nervosa ameliorates hyperactivity, three seriously ill females with hyperactivity …

This narrative review addressed to both clinicians and researchers aims to assess the role of
hypoleptinemia in disordered sleep with a particular focus on patients with anorexia nervosa …

This narrative review aims to pinpoint mental and behavioral effects of starvation, which may
be triggered by hypoleptinemia and as such may be amenable to treatment with leptin …

Leptin is an adipocyte-secreted hormone that plays a key part in energy homoeostasis.
Advances in leptin physiology have established that the main role of this hormone is to …

Body weight gain frequently occurs during drug treatment of psychiatric disorders and is
often accompanied by increased appetite or food craving. While occurrence and time course …