Exposure of P. gingivalis to noradrenaline reduces bacterial growth and elevates ArgX protease activity

T Saito, S Inagaki, K Sakurai, K Okuda, K Ishihara - Archives of oral biology, 2011 - Elsevier
OBJECTIVE: Periodontitis, an infectious disease caused by periodontopathic bacteria,
including Porphyromonas gingivalis and spirochetes, is reported to be accelerated by stress …

Signaling systems in oral bacteria

DP Miller, RJ Lamont - Oral Mucosal Immunity and Microbiome, 2019 - Springer
The supra-and subgingival plaque biofilm communities of plaque are composed of
hundreds of different microbes. These communities are spatially and temporally structured …

Deletion of Lipoprotein PG0717 in Porphyromonas gingivalis W83 Reduces Gingipain Activity and Alters Trafficking in and Response by Host Cells

L Reyes, E Eiler-McManis, PH Rodrigues, AS Chadda… - PloS one, 2013 - journals.plos.org
P. gingivalis (Pg), a causative agent of chronic generalized periodontitis, has been
implicated in promoting cardiovascular disease. Expression of lipoprotein gene PG0717 of …

Biofilm–substrate interaction: from initial adhesion to complex interactions and biofilm maturity

RM Love - Endodontic Topics, 2010 - Wiley Online Library
The bacteria‐related diseases of dental caries, pulp and periapical infections, and diseases
of the periodontium are biofilm diseases. Dental plaque exhibits the general properties of …

Transcriptional Regulation of Aggregatibacter actinomycetemcomitans lsrACDBFG and lsrRK Operons and Their Role in Biofilm Formation

A Torres-Escobar, MD Juárez-Rodríguez… - Journal of …, 2013 - Am Soc Microbiol
ABSTRACT Autoinducer-2 (AI-2) is required for biofilm formation and virulence of the oral
pathogen Aggregatibacter actinomycetemcomitans, and we previously showed that lsrB …

Expression of the short fimbriae of Porphyromonas gingivalis is regulated in oral bacterial consortia

Y Park, CE James, F Yoshimura… - FEMS microbiology …, 2006 - academic.oup.com
Abstract The Mfa1 protein of Porphyromonas gingivalis is the structural subunit of the short
fimbriae and mediates coadhesion between P. gingivalis and Streptococcus gordonii. We …

Survival of an Aggregatibacter actinomycetemcomitans quorum sensing luxS mutant in the mouths of Rhesus monkeys: insights into ecological adaptation

SK Velusamy, V Sampathkumar… - Molecular oral …, 2017 - Wiley Online Library
Experiments were designed to explore a prominent autoinducer‐2 (AI‐2) producing gene
(luxS) related to colonization and survival of Aggregatibacter actinomycetemcomitans, a low …

SigCH, an extracytoplasmic function sigma factor of Porphyromonas gingivalis regulates the expression of cdhR and hmuYR

K Ota, Y Kikuchi, K Imamura, D Kita, K Yoshikawa… - Anaerobe, 2017 - Elsevier
Extracytoplasmic function (ECF) sigma factors play an important role in the bacterial
response to various environmental stresses. Porphyromonas gingivalis, a prominent …

A novel small molecule, 1, 3-di-m-tolyl-urea, inhibits and disrupts multispecies oral biofilms

S Kalimuthu, BPK Cheung, JYY Yau, K Shanmugam… - Microorganisms, 2020 - mdpi.com
An imbalance of homeostasis between the microbial communities and the host system leads
to dysbiosis in oral micro flora. DMTU (1, 3-di-m-tolyl-urea) is a biocompatible compound …

Regulon controlled by the GppX hybrid two component system in Porphyromonas gingivalis

T Hirano, DAC Beck, CJ Wright… - Molecular oral …, 2013 - Wiley Online Library
The periodontal pathogen P orphyromonas gingivalis experiences a number of
environmental conditions in the oral cavity, and must monitor and respond to a variety of …