Social play is critical for the development of prefrontal inhibitory synapses and cognitive flexibility in rats

A Bijlsma, A Omrani, M Spoelder, JPH Verharen… - bioRxiv, 2020 - biorxiv.org
Sensory driven activity during early life is critical for setting up the proper connectivity of the
sensory cortices. Here we ask if social play behavior, a particular form of social interaction …

Brain substrates of behavioural endophenotypes predictive of compulsive drug-seeking

J Jones - 2022 - repository.cam.ac.uk
Addiction, also known as severe substance use disorder, is characterised by compulsive
drug-seeking and intake in the face of mounting adverse and negative consequences …

[图书][B] Impulsivity or Aversion to Ambiguity? Decision-Making under Uncertainty in Stimulant Use Disorder

ZR Guttman - 2021 - search.proquest.com
Stimulant misuse and dependence contribute substantially to the global burden of disease.
A major component of Stimulant Use Disorder (SUD) is maladaptive decision-making …

[图书][B] The Role of Mesolimbic Neural Dopamine Dynamics in Behavioral Individuation Towards Natural Reward and Drug

SE Montgomery - 2022 - search.proquest.com
Innate variability in response to rewarding stimuli is a striking but understudied phenomenon
that exists across species. Dopamine (DA) plays an integral role in the maintenance of …

[PDF][PDF] Adolescent THC impacts on mPFC dopamine-mediated cognitive processes in male and female rats

V Stephen - storage.prod.researchhub.com
Adolescent use of cannabis is linked to later-life changes in cognition, learning, and
memory. Rodent models suggest this could be a causal effect of Δ9-tetrahydrocannabinol …

Inhibition of ventral tegmental area projections to the nucleus accumbens shell increases premature responding in the 5-Choice serial reaction time task in rats

JP Flores-Dourojeanni, MH van den Munkhof… - 2022 - researchsquare.com
Exaggerated impulsivity and attentional impairments are hallmarks of certain disorders of
behavioural control such as attention-deficit/hyperactivity disorder (ADHD), schizophrenia …

Distinct roles for DAT and COMT in regulating dopamine transients and reward-guided decision making

C Korn, T Akam, KHR Jensen, C Vagnoni, A Huber… - BioRxiv, 2019 - biorxiv.org
Mechanisms for regulation of dopamine transmission are critical to its effects on behavior
and vary by region. Recycling via the dopamine transporter (DAT) predominates in striatum …

[引用][C] Unriddling the Neural Circuitry of Impulse Control

JP Flores Dourojeanni - 2019 - Utrecht University

Capturing Heightened Impulsivity In Adolescent Mice Using A T-Maze Delay Discounting Task

M Zhao - 2021 - search.proquest.com
Delay discounting is a well-established measure of heightened impulsive decision-making
during adolescence. The VTA and mPFC are implicated in delay discounting and undergo …

Impact du binge drinking sur les capacités de prise de décision chez le rat: rôle du sexe, du paradigme d'exposition à l'alcool et de la transmission dopaminergique …

P Sauton - 2020 - theses.hal.science
Le Binge Drinking (BD) est un mode de consommation d'alcool caractérisé par l'alternance
récurrente entre des épisodes d'intoxication intense et d'abstinence, pouvant entraîner des …