OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …

Intracranial aneurysm (IA) is a severe cerebrovascular disease characterized by abnormal
bulging of cerebral vessels that may rupture and cause a stroke. The expansion of the …

Background Inflammasome-mediated neuroinflammation plays an important role in the
pathogenesis of early brain injury (EBI) following subarachnoid hemorrhage (SAH). The …

Aneurysm wall remodeling (AWR) is an important pathological characteristic in aneurysm
wall, which was characterized by abnormal histological structure and inflammation …

Novel treatment strategies for cardiac tissue regeneration are heading for the use of
engineered cardiac tissue made from induced pluripotent stem cell-derived cardiomyocytes …

Background: Intracranial aneurysms (IAs) result from abnormal enlargement of the arterial
lumen. IAs are mostly quiescent and asymptomatic, but their rupture leads to severe brain …

Currently, the relationship of bifurcation morphology and aneurysm presence at the major
cerebral bifurcations is not clear. This study was to investigate cerebral arterial bifurcation …

Recent high-fidelity/resolution computational fluid dynamics simulations of intracranial
aneurysm hemodynamics have revealed turbulent-like flows. We hypothesized that the …

Purpose The morphological and hemodynamic features of patients with vertebral artery
dissecting aneurysms (VADAs) are yet unknown. This study sought to elucidate …

Hemodynamic stress and chronic inflammation are closely associated with the pathogenesis
of intracranial aneurysms (IAs). However, the hemodynamic and biological mechanisms …