Comprehensive morphomechanical analysis of brain aneurysms

A Raghuram, A Galloy, M Nino, S Sanchez… - Acta …, 2023 - Springer
Objective Brain aneurysms comprise different compartments that undergo unique biological
processes. A detailed multimodal analysis incorporating 3D aneurysm wall enhancement …

Investigation of paraclinoid aneurysm formation by comparing the combined influence of hemodynamic parameters between aneurysmal and non-aneurysmal arteries

H Yang, JJ Kim, YB Kim, KC Cho… - Journal of Cerebral …, 2024 - journals.sagepub.com
Numerous studies have evaluated the effects of hemodynamic parameters on aneurysm
formation. However, the reasons why aneurysms do not initiate in intracranial arteries are …

Low Wall Shear Stress and High Intra-Aneurysmal Pressure Are Associated with Ruptured Status of Vertebral Artery Dissecting Aneurysms

H Wei, K Yao, Q Tian, S Han, W Gao, W Han… - CardioVascular and …, 2023 - Springer
Purpose The morphological and hemodynamic features of patients with vertebral artery
dissecting aneurysms (VADAs) are yet unknown. This study sought to elucidate …

Imaging Inflammation–From Whole Body Imaging to Cellular Resolution

T Peñate Medina, JP Kolb, G Hüttmann… - Frontiers in …, 2021 - frontiersin.org
Imaging techniques have evolved impressively lately, allowing whole new concepts like
multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to …

Association of calcium channel blockers with lower incidence of intracranial aneurysm rupture and growth in hypertensive patients

Q Liu, J Li, Y Zhang, X Leng, M Mossa-Basha… - Journal of …, 2023 - thejns.org
OBJECTIVE Calcium channel blockers (CCBs) are antihypertensive agents with potential
vascular protection effects. This study investigated whether CCB usage was associated with …

Dedifferentiation of smooth muscle cells in intracranial aneurysms and its potential contribution to the pathogenesis

M Oka, S Shimo, N Ohno, H Imai, Y Abekura… - Scientific reports, 2020 - nature.com
Smooth muscle cells (SMCs) are the major type of cells constituting arterial walls and play a
role to maintain stiffness via producing extracellular matrix. Here, the loss and degenerative …

Computational fluid dynamic analysis of the initiation of cerebral aneurysms

S Fujimura, K Tanaka, H Takao, T Okudaira… - Journal of …, 2021 - thejns.org
OBJECTIVE Relationships between aneurysm initiation and hemodynamic factors remain
unclear since de novo aneurysms are rarely observed. Most previous computational fluid …

Potential role of endothelial progenitor cells in the pathogenesis and treatment of cerebral aneurysm

J Yu, Q Du, X Li, W Wei, Y Fan, J Zhang… - Frontiers in Cellular …, 2024 - frontiersin.org
Cerebral aneurysm (CA) is a significant health concern that results from pathological
dilations of blood vessels in the brain and can lead to severe and potentially life-threatening …

A review of intracranial aneurysm imaging modalities, from CT to state-of-the-art MR

S Allaw, K Khabaz, TC Given, DM Montas… - American Journal of …, 2024 - ajnr.org
Traditional guidance for intracranial aneurysm (IA) management is dichotomized by rupture
status. Fundamental to ruptured aneurysm management is the detection and treatment of …

Eicosapentaenoic acid prevents the progression of intracranial aneurysms in rats

Y Abekura, I Ono, A Kawashima, K Takizawa… - Journal of …, 2020 - Springer
Background As subarachnoid hemorrhage due to rupture of an intracranial aneurysm (IA)
has quite a poor outcome despite of an intensive medical care, development of a novel …