Massive apixaban overdose confirmed with blood concentrations and managed without bleeding: A single case report

E Harmouche, P Stueve… - Journal of Pharmacy …, 2024 - journals.sagepub.com
Background: Acute overdoses of apixaban, and other direct oral anticoagulants are
relatively uncommon. The number of direct oral anticoagulants prescriptions in the United …

Administration of andexanet alfa for traumatic intracranial hemorrhage in the setting of massive apixaban overdose: A case report

D Jenniches, AF Kerns, J DelBianco… - American Journal of …, 2023 - academic.oup.com
Purpose Apixaban is a direct-acting oral anticoagulant that selectively inhibits factor Xa.
Reversal strategies utilized to treat factor Xa inhibitor–associated bleeding include …

Case series of massive direct oral anticoagulant ingestion—Treatment and pharmacokinetics data

M Delrue, L Chevillard, A Stépanian… - European Journal of …, 2022 - Wiley Online Library
Background Direct oral anticoagulants (DOAC) are widely used due to favourable
benefit/risk ratio. However, consequences of massive ingestion have been poorly …

Accidental apixaban intoxication in a 23-month-old child: a case report

M Launay, Y Nasser, I Maubert, AC Chaux… - BMC pediatrics, 2020 - Springer
Background Direct oral anticoagulants, such as apixaban, are increasingly used in everyday
practice in order to treat or prevent thromboembolic diseases. To date, there is no available …

Complete investigations (autopsy, toxicology, and histology) in a death due to apixaban overdose

P Kintz, C Allain, L Oertel, E Feisthauer… - International journal of …, 2023 - Springer
The dead body of a 54-year-old man was found at home by his partner. He was off work due
to depression. A letter with suicidal intention was present on the scene. He was known to be …