Toward a macaque model of HIV-1 infection: Roadblocks, progress, and future strategies
The human-specific tropism of Human Immunodeficiency Virus Type 1 (HIV-1) has
complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for …
complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for …
How host genetics dictates successful viral zoonosis
Viruses of wild and domestic animals can infect humans in a process called zoonosis, and
these events can give rise to explosive epidemics such as those caused by the HIV and …
these events can give rise to explosive epidemics such as those caused by the HIV and …
Latest animal models for anti-HIV drug discovery
K Sliva - Expert opinion on drug discovery, 2015 - Taylor & Francis
Introduction: HIV research is limited by the fact that lentiviruses are highly species specific.
The need for appropriate models to promote research has led to the development of many …
The need for appropriate models to promote research has led to the development of many …
Selective use of primate CD4 receptors by HIV-1
CJ Warren, NR Meyerson, O Dirasantha… - PLoS …, 2019 - journals.plos.org
Individuals chronically infected with HIV-1 harbor complex viral populations within their
bloodstreams. Recently, it has come to light that when these people infect others, the new …
bloodstreams. Recently, it has come to light that when these people infect others, the new …
In vivo Serial Passaging of Human–Simian Immunodeficiency Virus Clones Identifies Characteristics for Persistent Viral Replication
R Thippeshappa, P Polacino… - Frontiers in …, 2021 - frontiersin.org
We previously reported that a human immunodeficiency virus type 1 with a simian
immunodeficiency virus vif substitution (HSIV-vifNL4-3) could replicate in pigtailed …
immunodeficiency virus vif substitution (HSIV-vifNL4-3) could replicate in pigtailed …
Animal model studies on viral infections
A Adachi, T Miura - Frontiers in Microbiology, 2014 - frontiersin.org
One of the major missions of animal virology is to understand how viruses replicate and
cause asymptomatic/symptomatic conditions in individuals (Nomaguchi and Adachi, 2010) …
cause asymptomatic/symptomatic conditions in individuals (Nomaguchi and Adachi, 2010) …
Development of a novel Macaque-Tropic HIV-1 adapted to cynomolgus macaques
H Ode, A Saito, A Washizaki, Y Seki… - Journal of General …, 2022 - microbiologyresearch.org
Macaque-tropic HIV-1 (HIV-1mt) variants have been developed to establish preferable
primate models that are advantageous in understanding HIV-1 infection pathogenesis and …
primate models that are advantageous in understanding HIV-1 infection pathogenesis and …
Understanding restriction factors and intrinsic immunity: insights and lessons from the primate lentiviruses
A Kirmaier, A Krupp, WE Johnson - Future virology, 2014 - Taylor & Francis
Primate lentiviruses include the HIVs, HIV-1 and HIV-2; the SIVs, which are endemic to more
than 40 species of nonhuman primates in Africa; and SIVmac, an AIDS-causing pathogen …
than 40 species of nonhuman primates in Africa; and SIVmac, an AIDS-causing pathogen …
B-cells and the use of non-human primates for evaluation of HIV vaccine candidates
T Demberg, M Robert-Guroff - Current HIV Research, 2015 - ingentaconnect.com
The RV144 clinical trial in Thailand associated vaccine-induced antibodies with protective
efficacy, leading to a focus in HIV vaccine research on protective antibody induction. This …
efficacy, leading to a focus in HIV vaccine research on protective antibody induction. This …
[HTML][HTML] HIV-1 Replication and Pathogenicity: Lessons from Macaque-Tropic HIV-1 Derivatives
T Koma, N Doi, BQ Le, T Kondo, A Adachi… - … Immune Response to …, 2023 - intechopen.com
Human immunodeficiency virus type 1 (HIV-1) is tropic for humans and replicates in virtually
none of the other animal species. While various animal models to mimic the conflict between …
none of the other animal species. While various animal models to mimic the conflict between …