Allogeneic haematopoietic cell transplantation for myelofibrosis: proposed definitions and management strategies for graft failure, poor graft function and relapse: best …

DP McLornan, JC Hernandez-Boluda, T Czerw… - Leukemia, 2021 - nature.com
Allogeneic haematopoietic cell transplantation (allo-HCT) remains the only curative
approach in myelofibrosis (MF). Despite advances over recent decades, relapse and non …

Chimerism analysis for clinicians: a review of the literature and worldwide practices

AG Blouin, M Askar - Bone marrow transplantation, 2022 - nature.com
This review highlights literature pertinent to chimerism analysis in the context of
hematopoietic cell transplantation (HCT). We also conducted a survey of testing practices of …

Treosulfan compared to busulfan in allogeneic haematopoietic stem cell transplantation for myelofibrosis: a registry-based study from the Chronic Malignancies …

M Robin, S Iacobelli, L Koster, J Passweg… - Bone Marrow …, 2024 - nature.com
We aimed to compare outcomes following treosulfan (TREO) or busulfan (BU) conditioning
in a large cohort of myelofibrosis (MF) patients from the EBMT registry. A total of 530 patients …

Incomplete chimerism following myeloablative and anti-thymocyte globulin-conditioned hematopoietic cell transplantation is a risk factor for relapse and chronic graft …

RA Khanolkar, G Tripathi, P Dharmani-Khan, R Dabas… - Cytotherapy, 2022 - Elsevier
Background aims The value of routine chimerism determination after myeloablative
hematopoietic cell transplantation (HCT) is unclear, particularly in the setting of anti …

Long-term survival with mixed chimerism in patients with AML and MDS transplanted after conditioning with targeted busulfan, fludarabine, and thymoglobulin

AC Yeh, PV O'Donnell, G Schoch, PJ Martin… - Bone marrow …, 2022 - nature.com
We evaluated long-term outcome in 40 patients with MDS or AML, transplanted from related
or unrelated donors following conditioning with targeted busulfan (Bu, over 4 days) …

Chimerism, the microenvironment and control of leukemia

HJ Deeg - Frontiers in immunology, 2021 - frontiersin.org
Transplantation of allogeneic hematopoietic cells faces two barriers: failure of engraftment
due to a host versus graft reaction, and the attack of donor cells against the patient, the graft …

Donor Lymphocyte Infusion (DLI) post allogeneic stem cell transplant (allo-SCT) in Acute Myeloid Leukemia (AML) and High-Grade Myelodysplastic Syndrome (MDS) …

T Indran, T Das, J Muirhead, M O'Brien, MI Swain… - Leukemia Research, 2024 - Elsevier
Introduction This longitudinal study was based on the outcomes of Donor Lymphocyte
Infusion (DLI) for falling peripheral blood (PB) CD34+ and CD3+ donor chimerism (DC) …

Effect of pre‐transplant JAK1/2 inhibitors and CD34 dose on transplant outcomes in myelofibrosis

S Cyriac, S Prem, MQ Salas, S Chen… - European Journal of …, 2021 - Wiley Online Library
Allogeneic hematopoeitic cell transplantation (allo‐HCT) is the only curative treatment for
myelofibrosis (MF). We evaluate the impact of various factors on survival outcomes post …

Long-Term Mixed Chimerism After Ex Vivo/In Vivo T Cell-Depleted Allogeneic Hematopoietic Cell Transplantation in Patients With Myeloid Neoplasms

L Ruhnke, F Stölzel, U Oelschlägel, M von Bonin… - Frontiers in …, 2021 - frontiersin.org
In patients who have undergone allogeneic hematopoietic cell transplantation (HCT),
myeloid mixed donor chimerism (MC) is a risk factor for disease relapse. In contrast, several …

[HTML][HTML] Мониторинг химеризма после трансплантации аллогенных гемопоэтических стволовых клеток

ДС Дубняк, НВ Рисинская, МЮ Дроков… - …, 2022 - cyberleninka.ru
Трансплантация аллогенных гемопоэтических стволовых клеток является одним из
эффективных методовлечения пациентов с заболеваниями системы крови. Среди …