Iron overload is a systemic disorder and is either primary (genetic) or secondary (exogenous
iron administration). Primary iron overload is most commonly associated with hereditary …

Introduction. Amiodarone has been used for more than 5 decades for the treatment of
various tachyarrhythmias and previously for the treatment of refractory angina. There are …

Ventricular arrhythmias still represent an important cause of morbidity and mortality,
especially in patients with heart failure and reduced left ventricular ejection fraction …

Drug-induced mitochondrial toxicity is a contributing factor to many organ toxicities. The fact
that some, but not all members of a particular drug class can induce mitochondrial …

[8] Li Y, Li WM, Gong YT, et al. The effects of cilazapril and valsartan on the mRNA and
protein expressions of atrial calpains and atrial structural remodeling in atrial fibrillation …

A60-year-old man with medical history of atrial fibrillation on amiodarone 400 mg/d for 8
years was admitted for increased shortness of breath. On his general physical examination …

Purpose To evaluate CT density of liver changes between before and after amiodarone
administration. Materials and methods Twenty-five patients underwent non-enhanced CT …

Amiodarone accumulates in the liver, where it increases x-ray attenuation due to its iodine
content. We evaluated liver attenuation in patients treated and not treated with amiodarone …

Abstract Drug-induced phospholipidosis (DIPLD), characterized by the accumulation of
phospholipids within lysosomes, is suspected to impair lysosomal function and considered …

There are a variety of less common diffuse liver diseases that can be asymptomatic or cause
severe liver dysfunction. For the majority of them, the association of clinical, laboratory, and …