[HTML][HTML] Estrogens, cancer and immunity
I Orzołek, J Sobieraj, J Domagała-Kulawik - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present current knowledge of sex hormones in the
process of development of malignant diseases. The impact of sex hormones on immune …
process of development of malignant diseases. The impact of sex hormones on immune …
Applications of CRISPR/Cas9 technology in the treatment of lung cancer
C Jiang, X Lin, Z Zhao - Trends in molecular medicine, 2019 - cell.com
Since its emergence, the application of CRISPR-associated nuclease 9 (Cas9) technology
in cancer research has accelerated studies to investigate many aspects of treatment …
in cancer research has accelerated studies to investigate many aspects of treatment …
[HTML][HTML] Targeting Nuclear Receptors in Lung Cancer—Novel Therapeutic Prospects
Lung cancer, the second most commonly diagnosed cancer, is the major cause of fatalities
worldwide for both men and women, with an estimated 2.2 million new incidences and 1.8 …
worldwide for both men and women, with an estimated 2.2 million new incidences and 1.8 …
[HTML][HTML] Cytoplasmic expression of G protein-coupled estrogen receptor 1 correlates with poor postoperative prognosis in non-small cell lung cancer
ZH Li, C Liu, QH Liu, J Wang, Y Wang… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Background A hormonal role in the development of non-small cell lung cancer (NSCLC) has
been well documented, and the classic estrogen receptors (ERs)—ERα and ERβ have been …
been well documented, and the classic estrogen receptors (ERs)—ERα and ERβ have been …
[HTML][HTML] New Perspectives on Sex Steroid Hormones Signaling in Cancer-Associated Fibroblasts of Non-Small Cell Lung Cancer
C Inoue, Y Miki, T Suzuki - Cancers, 2023 - mdpi.com
Simple Summary Non-small cell lung cancer (NSCLC) is the most common type of lung
cancer. Smoking is a major risk factor for NSCLC; however, the incidence of NSCLC among …
cancer. Smoking is a major risk factor for NSCLC; however, the incidence of NSCLC among …
[HTML][HTML] Upregulation of estrogen receptor beta protein but not mRNA predicts poor prognosis and may be associated with enhanced translation in non-small cell lung …
W Meng, Y Liao, J Chen, Y Wang, Y Meng… - Journal of thoracic …, 2021 - ncbi.nlm.nih.gov
Background An increasing number of original studies suggest that estrogen receptor beta
(ERβ) expression may be related to non-small cell lung cancer (NSCLC) prognosis; …
(ERβ) expression may be related to non-small cell lung cancer (NSCLC) prognosis; …
PELP1 is overexpressed in lung cancer and promotes tumor cell malignancy and resistance to tyrosine kinase inhibitor drug
X Wang, W Yin, L Liang - Pathology-Research and Practice, 2022 - Elsevier
Proline, glutamate, and leucine-rich protein 1 (PELP1) are involved in several cancers, but
little is known about PELP1 in lung cancer. In this study, PELP1 expression was evaluated in …
little is known about PELP1 in lung cancer. In this study, PELP1 expression was evaluated in …
[HTML][HTML] Estrogen Receptor Beta Prevents Signet Ring Cell Gastric Carcinoma Progression in Young Patients by Inhibiting Pseudopodia Formation via the mTOR …
X Wang, X Xia, E Xu, Z Yang, X Shen, S Du… - Frontiers in Cell and …, 2021 - frontiersin.org
Signet ring cell gastric carcinoma (SRCGC) is a poorly differentiated malignancy, and can
be highly dangerous in the progression stage. There is a higher male to female ratio among …
be highly dangerous in the progression stage. There is a higher male to female ratio among …
[HTML][HTML] Systematic omics analysis identifies CCR6 as a therapeutic target to overcome cancer resistance to EGFR inhibitors
Epidermal growth factor receptor inhibitors (EGFRi) have exhibited promising clinical
outcomes in the treatment of various cancers. However, their widespread application has …
outcomes in the treatment of various cancers. However, their widespread application has …
Exosomes from irradiated nonsmall cell lung cancer cells reduced sensitivity of recipient cells to anaplastic lymphoma kinase inhibitors
H Wu, C Zeng, Y Ye, J Liu, Z Mu, Y Xie… - Molecular …, 2018 - ACS Publications
Exosomes, released from various cell types, serve as vehicles of intercellular
communication. Rearranged anaplastic lymphoma kinase (ALK) has been detected in …
communication. Rearranged anaplastic lymphoma kinase (ALK) has been detected in …