[HTML][HTML] Estrogens, cancer and immunity

I Orzołek, J Sobieraj, J Domagała-Kulawik - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present current knowledge of sex hormones in the
process of development of malignant diseases. The impact of sex hormones on immune …

Applications of CRISPR/Cas9 technology in the treatment of lung cancer

C Jiang, X Lin, Z Zhao - Trends in molecular medicine, 2019 - cell.com
Since its emergence, the application of CRISPR-associated nuclease 9 (Cas9) technology
in cancer research has accelerated studies to investigate many aspects of treatment …

[HTML][HTML] Targeting Nuclear Receptors in Lung Cancer—Novel Therapeutic Prospects

SK Gangwar, A Kumar, KCH Yap, S Jose, D Parama… - Pharmaceuticals, 2022 - mdpi.com
Lung cancer, the second most commonly diagnosed cancer, is the major cause of fatalities
worldwide for both men and women, with an estimated 2.2 million new incidences and 1.8 …

[HTML][HTML] Cytoplasmic expression of G protein-coupled estrogen receptor 1 correlates with poor postoperative prognosis in non-small cell lung cancer

ZH Li, C Liu, QH Liu, J Wang, Y Wang… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Background A hormonal role in the development of non-small cell lung cancer (NSCLC) has
been well documented, and the classic estrogen receptors (ERs)—ERα and ERβ have been …

[HTML][HTML] New Perspectives on Sex Steroid Hormones Signaling in Cancer-Associated Fibroblasts of Non-Small Cell Lung Cancer

C Inoue, Y Miki, T Suzuki - Cancers, 2023 - mdpi.com
Simple Summary Non-small cell lung cancer (NSCLC) is the most common type of lung
cancer. Smoking is a major risk factor for NSCLC; however, the incidence of NSCLC among …

[HTML][HTML] Upregulation of estrogen receptor beta protein but not mRNA predicts poor prognosis and may be associated with enhanced translation in non-small cell lung …

W Meng, Y Liao, J Chen, Y Wang, Y Meng… - Journal of thoracic …, 2021 - ncbi.nlm.nih.gov
Background An increasing number of original studies suggest that estrogen receptor beta
(ERβ) expression may be related to non-small cell lung cancer (NSCLC) prognosis; …

PELP1 is overexpressed in lung cancer and promotes tumor cell malignancy and resistance to tyrosine kinase inhibitor drug

X Wang, W Yin, L Liang - Pathology-Research and Practice, 2022 - Elsevier
Proline, glutamate, and leucine-rich protein 1 (PELP1) are involved in several cancers, but
little is known about PELP1 in lung cancer. In this study, PELP1 expression was evaluated in …

[HTML][HTML] Estrogen Receptor Beta Prevents Signet Ring Cell Gastric Carcinoma Progression in Young Patients by Inhibiting Pseudopodia Formation via the mTOR …

X Wang, X Xia, E Xu, Z Yang, X Shen, S Du… - Frontiers in Cell and …, 2021 - frontiersin.org
Signet ring cell gastric carcinoma (SRCGC) is a poorly differentiated malignancy, and can
be highly dangerous in the progression stage. There is a higher male to female ratio among …

[HTML][HTML] Systematic omics analysis identifies CCR6 as a therapeutic target to overcome cancer resistance to EGFR inhibitors

EJ Kwon, HJ Cha, H Lee - Iscience, 2024 - cell.com
Epidermal growth factor receptor inhibitors (EGFRi) have exhibited promising clinical
outcomes in the treatment of various cancers. However, their widespread application has …

Exosomes from irradiated nonsmall cell lung cancer cells reduced sensitivity of recipient cells to anaplastic lymphoma kinase inhibitors

H Wu, C Zeng, Y Ye, J Liu, Z Mu, Y Xie… - Molecular …, 2018 - ACS Publications
Exosomes, released from various cell types, serve as vehicles of intercellular
communication. Rearranged anaplastic lymphoma kinase (ALK) has been detected in …