Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019
Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …
and biological information in order to optimise the therapeutic benefit relative to the …
Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
by an acute deterioration in respiratory symptoms, are fundamental events impacting …
Pharmacologic management of chronic obstructive pulmonary disease. An official American Thoracic Society clinical practice guideline
Background: This document provides clinical recommendations for the pharmacologic
treatment of chronic obstructive pulmonary disease (COPD). It represents a collaborative …
treatment of chronic obstructive pulmonary disease (COPD). It represents a collaborative …
Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials
M Bafadhel, S Peterson, MA De Blas… - The Lancet …, 2018 - thelancet.com
Background The peripheral blood eosinophil count might help identify those patients with
chronic obstructive pulmonary disease (COPD) who will experience fewer exacerbations …
chronic obstructive pulmonary disease (COPD) who will experience fewer exacerbations …
Exacerbations of COPD
C Viniol, CF Vogelmeier - European Respiratory Review, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer …
worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer …
Inflammatory endotypes in COPD
PJ Barnes - Allergy, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …
poorly treated by current therapies as it has proved difficult to treat the underlying …
Diagnosis and outpatient management of chronic obstructive pulmonary disease: a review
CM Riley, FC Sciurba - Jama, 2019 - jamanetwork.com
Importance There are 30 million adults (12%) in the United States who have chronic
obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease accounts for …
obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease accounts for …
Inhaled corticosteroids in COPD: friend or foe?
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …
Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort
AT Hastie, FJ Martinez, JL Curtis… - The Lancet …, 2017 - thelancet.com
Background Increased concentrations of eosinophils in blood and sputum in chronic
obstructive pulmonary disease (COPD) have been associated with increased frequency of …
obstructive pulmonary disease (COPD) have been associated with increased frequency of …
Long-term triple therapy de-escalation to indacaterol/glycopyrronium in patients with chronic obstructive pulmonary disease (SUNSET): a randomized, double-blind …
KR Chapman, JR Hurst, SM Frent, M Larbig… - American journal of …, 2018 - atsjournals.org
Rationale: There are no studies on withdrawal of inhaled corticosteroids in patients on long-
term triple therapy in the absence of frequent exacerbations. Objectives: To evaluate the …
term triple therapy in the absence of frequent exacerbations. Objectives: To evaluate the …