The role of the transcription factor Ets1 in carcinoma
J Dittmer - Seminars in cancer biology, 2015 - Elsevier
Ets1 belongs to the large family of the ETS domain family of transcription factors and is
involved in cancer progression. In most carcinomas, Ets1 expression is linked to poor …
involved in cancer progression. In most carcinomas, Ets1 expression is linked to poor …
Increased oxidative stress as a selective anticancer therapy
J Liu, Z Wang - Oxidative medicine and cellular longevity, 2015 - Wiley Online Library
Reactive oxygen species (ROS) are closely related to tumorgenesis. Under hypoxic
environment, increased levels of ROS induce the expression of hypoxia inducible factors …
environment, increased levels of ROS induce the expression of hypoxia inducible factors …
Single‐cell transcriptomic analysis of primary and metastatic tumor ecosystems in esophageal squamous cell carcinoma
Y Jia, B Zhang, C Zhang, DLW Kwong… - Advanced …, 2023 - Wiley Online Library
Lymph node metastasis, the leading cause of mortality in esophageal squamous carcinoma
(ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the …
(ESCC) with a highly complex tumor microenvironment, remains underexplored. Here, the …
Molecular and cellular mechanisms controlling integrin-mediated cell adhesion and tumor progression in ovarian cancer metastasis: a review
D Dhaliwal, TG Shepherd - Clinical & Experimental Metastasis, 2022 - Springer
Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy in the
developed world. EOC metastasis is unique since malignant cells detach directly from the …
developed world. EOC metastasis is unique since malignant cells detach directly from the …
The molecular markers of cancer stem cells in head and neck tumors
SS Yu, N Cirillo - Journal of cellular physiology, 2020 - Wiley Online Library
Head and neck cancer (HNC) is the six most common malignancy worldwide leading to
more than 350,000 deaths annually. Despite recent advances in treatment modalities for …
more than 350,000 deaths annually. Despite recent advances in treatment modalities for …
THY1-mediated mechanisms converge to drive YAP activation in skin homeostasis and repair
E Sedov, E Koren, S Chopra, R Ankawa… - Nature Cell …, 2022 - nature.com
Anchored cells of the basal epidermis constantly undergo proliferation in an overcrowded
environment. An important regulator of epidermal proliferation is YAP, which can be …
environment. An important regulator of epidermal proliferation is YAP, which can be …
CD90/Thy-1, a cancer-associated cell surface signaling molecule
C Sauzay, K Voutetakis, A Chatziioannou… - Frontiers in cell and …, 2019 - frontiersin.org
CD90 is a membrane GPI-anchored protein with one Ig V-type superfamily domain that was
initially described in mouse T cells. Besides the specific expression pattern and functions of …
initially described in mouse T cells. Besides the specific expression pattern and functions of …
MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF
B Li, WW Xu, L Han, KT Chan, SW Tsao, NPY Lee… - Oncogene, 2017 - nature.com
Esophageal cancer is one of the most lethal cancers worldwide with poor survival and
limited therapeutic options. The discovery of microRNAs created a new milestone in cancer …
limited therapeutic options. The discovery of microRNAs created a new milestone in cancer …
Multiple roles of CD90 in cancer
Abstract THY1 (CD90) is a 25–37-kDa heavily N-glycosylated, glycophosphatidylinositol
(GPI) anchored cell surface protein. It is usually expressed on thymocytes, mesenchymal …
(GPI) anchored cell surface protein. It is usually expressed on thymocytes, mesenchymal …
[HTML][HTML] ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma
L Yang, Y Ren, X Yu, F Qian, H Xiao, W Wang, S Xu… - Modern Pathology, 2014 - Elsevier
Invasion and metastasis are the major cause of deaths in patients with esophageal cancer.
In this study, we isolated cancer stem-like cells from an esophageal squamous cell …
In this study, we isolated cancer stem-like cells from an esophageal squamous cell …