The ability of the pluripotent epiblast to contribute progeny to all three germ layers is thought
to be lost after gastrulation. The later-forming neural crest (NC) rises from ectoderm and it …

Simple Summary Neural crest cells are unique to vertebrates and migrate long distances
throughout the embryo and give rise to many cell and tissue types, including bone, cartilage …

Mesenchymal stem/stromal cells (MSCs) are found in almost all postnatal organs. Under
appropriate environmental cues, multipotency enables MSCs to serve as progenitors for …

Bioenergetic metabolism is a key regulator of cellular function and signaling, but how it can
instruct the behavior of cells and their fate during embryonic development remains largely …

Pax3/7 factors play numerous roles in the development of the dorsal nervous system of
vertebrates. From specifying neural crest at the neural plate borders, to regulating neural …

Neural-crest cells and neuromesodermal progenitors (NMPs) are multipotent cells that are
important for development of vertebrate embryos. In embryos of ascidians, which are the …

The ability of the pluripotent epiblast to contribute progeny to all three germ layers is thought
to be lost after gastrulation. The later-forming neural crest (NC) rises from ectoderm and it …