Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …

The neurovascular unit (NVU) comprises brain endothelial cells, pericytes or vascular
smooth muscle cells, glia and neurons. The NVU controls blood–brain barrier (BBB) …

Glucose transporters (GLUTs) at the blood-brain barrier maintain the continuous high
glucose and energy demands of the brain. They also act as therapeutic targets and provide …

A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise,
may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords …

Neurovascular dysfunction contributes to A lzheimer's disease (AD). Cerebrovascular
abnormalities and blood–brain barrier (BBB) damage have been shown in AD. The BBB …

Frailty is a complex and heterogeneous clinical syndrome. Cognitive frailty has been
considered as a subtype of frailty. In this study, we refine the definition of cognitive frailty …

Background—Studies have linked midlife and late-life cardiovascular risk factors (CVRFs) to
cognitive function, yet little is known about CVRF exposure in early adulthood and …

To determine incidence of dementia in type 2 diabetic (T2DM) patients, and whether there
are adverse or favorable effects of oral agents (OA) in DM, we obtained a representative …

Alzheimer's disease (AD) is an age-related disorder characterized by progressive cognitive
decline and dementia. Alzheimer's disease is an increasingly prevalent disease with 5.3 …

There is accumulating evidence suggesting that changes in brain perfusion are present long
before the clinical symptoms of Alzheimer's disease (AD), perhaps even before amyloid-β …