Neutrophil diversity and plasticity in tumour progression and therapy
Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …
[HTML][HTML] Tumor-associated neutrophils and neutrophil-targeted cancer therapies
H Que, Q Fu, T Lan, X Tian, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …
range of inflammatory disorders in the body. In recent years, neutrophils have gained …
Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis
YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
Neutrophil extracellular traps: from physiology to pathology
At the frontline of the host defence response, neutrophil antimicrobial functions have
adapted to combat infections and injuries of different origins and magnitude. The release of …
adapted to combat infections and injuries of different origins and magnitude. The release of …
Neutrophils as potential therapeutic targets in hepatocellular carcinoma
The success of atezolizumab plus bevacizumab treatment contributed to a shift in systemic
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
therapies for hepatocellular carcinoma (HCC) towards combinations that include cancer …
Tumor associated neutrophils. Their role in tumorigenesis, metastasis, prognosis and therapy
MT Masucci, M Minopoli, MV Carriero - Frontiers in oncology, 2019 - frontiersin.org
Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by
cytokines and chemokines, can be distinguished according to their activation and cytokine …
cytokines and chemokines, can be distinguished according to their activation and cytokine …
Nanotechnology for boosting cancer immunotherapy and remodeling tumor microenvironment: the horizons in cancer treatment
S Gao, X Yang, J Xu, N Qiu, G Zhai - ACS nano, 2021 - ACS Publications
Immunotherapy that harnesses the human immune system to fight cancer has received
widespread attention and become a mainstream strategy for cancer treatment. Cancer …
widespread attention and become a mainstream strategy for cancer treatment. Cancer …
The neutrophil's role during health and disease
Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
Lactic acid and an acidic tumor microenvironment suppress anticancer immunity
JX Wang, SYC Choi, X Niu, N Kang, H Xue… - International journal of …, 2020 - mdpi.com
Immune evasion and altered metabolism, where glucose utilization is diverted to increased
lactic acid production, are two fundamental hallmarks of cancer. Although lactic acid has …
lactic acid production, are two fundamental hallmarks of cancer. Although lactic acid has …
Neutrophil hitchhiking for drug delivery to the bone marrow
Z Luo, Y Lu, Y Shi, M Jiang, X Shan, X Li… - Nature …, 2023 - nature.com
Pharmaceuticals have been developed for the treatment of a wide range of bone diseases
and disorders, but suffer from problematic delivery to the bone marrow. Neutrophils are …
and disorders, but suffer from problematic delivery to the bone marrow. Neutrophils are …